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Merck
CN

469963

L-Threoninol

97%, for peptide synthesis

Synonym(s):

(2R,3R)-2-Amino-1,3-butanediol

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About This Item

Linear Formula:
CH3CH(OH)CH(NH2)CH2OH
CAS Number:
Molecular Weight:
105.14
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
6130524
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Product Name

L-Threoninol, 97%

Quality Level

assay

97%

form

solid

optical activity

[α]20/D −4.2°, c = 1% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

49-54 °C (lit.)

application(s)

peptide synthesis

SMILES string

C[C@@H](O)[C@H](N)CO

InChI

1S/C4H11NO2/c1-3(7)4(5)2-6/h3-4,6-7H,2,5H2,1H3/t3-,4-/m1/s1

InChI key

MUVQIIBPDFTEKM-QWWZWVQMSA-N

General description

L-Threoninol also known as (2R,3R)-2-Amino-1,3-butanediol, is an amino alcohol, which is commonly used in solution phase peptide synthesis.

Application

L-Threoninol can be used as artificial abasic nucleoside in the synthesis and modification of oligodeoxynucleotide and can also be utilized to synthesize pyrene-L-threoninyl analogues.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Synthesis and properties of an oligonucleotide modified with an acridine derivative at the artificial abasic site
K Fukui
Bioconjugate Chemistry, 7, 349-355 (1996)
Potent triple helix stabilization by 5?, 3?-modified triplex-forming oligonucleotides
N Ben Gaied
Chembiochem, 10, 1839-1851 (2009)



Global Trade Item Number

SKUGTIN
469963-1G04061832359229