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Merck
CN

47587

Fmoc-β-Ala-OH

≥99.0% (HPLC)

Synonym(s):

Fmoc-β-alanine

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About This Item

Empirical Formula (Hill Notation):
C18H17NO4
CAS Number:
Molecular Weight:
311.33
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
2302327
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Quality Level

assay

≥99.0% (HPLC)

form

powder or crystals

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

142-147 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)CCNC(=O)OCC1c2ccccc2-c3ccccc13

InChI

1S/C18H17NO4/c20-17(21)9-10-19-18(22)23-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,19,22)(H,20,21)

InChI key

LINBWYYLPWJQHE-UHFFFAOYSA-N

General description

Fmoc-β-Ala-OH also known as Fmoc-β-alanine, is a versatile reagent for solid phase peptide synthesis.

Application

Fmoc-β-Ala-OH is used as a linker to synthesize peptides on a monolithic GMA-EDMA (glycidyl methacrylate-co-ethylene dimethacrylate) matrix via Fmoc solid phase peptide synthesis.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Solid phase peptide synthesis on epoxy-bearing methacrylate monoliths
E Vlakh
Journal of Peptide Science, 10, 719-730 (2004)
Sofie Trier et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 329-337 (2015-09-09)
Acylation of peptide drugs with fatty acid chains has proven beneficial for prolonging systemic circulation, as well as increasing enzymatic stability and interactions with lipid cell membranes. Thus, acylation offers several potential benefits for oral delivery of therapeutic peptides, and



Global Trade Item Number

SKUGTIN
47587-5G-F04061832361963
47587-25G-F04061832594897