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Merck
CN

47703

Fmoc-Glu(OAll)-OH

≥96.0% (HPLC)

Synonym(s):

Fmoc-L-glutamic acid 5-allyl ester

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About This Item

Empirical Formula (Hill Notation):
C23H23NO6
CAS Number:
Molecular Weight:
409.43
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6670846
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Product Name

Fmoc-Glu(OAll)-OH, ≥96.0% (HPLC)

InChI

1S/C23H23NO6/c1-2-13-29-21(25)12-11-20(22(26)27)24-23(28)30-14-19-17-9-5-3-7-15(17)16-8-4-6-10-18(16)19/h2-10,19-20H,1,11-14H2,(H,24,28)(H,26,27)/t20-/m0/s1

SMILES string

OC(=O)[C@H](CCC(=O)OCC=C)NC(=O)OCC1c2ccccc2-c3ccccc13

InChI key

LRBARFFNYOKIAX-FQEVSTJZSA-N

assay

≥96.0% (HPLC)

optical activity

[α]20/D −16.5±2°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

Quality Level

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Ashley E Lepack et al.
Science (New York, N.Y.), 368(6487), 197-201 (2020-04-11)
Vulnerability to relapse during periods of attempted abstinence from cocaine use is hypothesized to result from the rewiring of brain reward circuitries, particularly ventral tegmental area (VTA) dopamine neurons. How cocaine exposures act on midbrain dopamine neurons to precipitate addiction-relevant
Lorna A Farrelly et al.
Nature, 567(7749), 535-539 (2019-03-15)
Chemical modifications of histones can mediate diverse DNA-templated processes, including gene transcription1-3. Here we provide evidence for a class of histone post-translational modification, serotonylation of glutamine, which occurs at position 5 (Q5ser) on histone H3 in organisms that produce serotonin

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