Skip to Content
Merck
CN

49510

L-Glutamic acid γ-benzyl ester

≥99.0% (T)

Synonym(s):

L-Glutamic acid 5-benzyl ester

Sign In to View Organizational & Contract Pricing

Select a Size

About This Item

Linear Formula:
C6H5CH2OCOCH2CH2CH(NH2)COOH
CAS Number:
1676-73-9
Molecular Weight:
237.25
Beilstein:
1885646
EC Number:
216-826-1
MDL number:
MFCD00002633
UNSPSC Code:
12352209
PubChem Substance ID:
57651200
NACRES:
NA.22

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

100

Assay

≥99.0% (T)

optical activity

[α]20/D +19±2°, c = 1% in acetic acid

reaction suitability

reaction type: solution phase peptide synthesis

mp

181-182 °C (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(=O)OCc1ccccc1)C(O)=O

InChI

1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1

InChI key

BGGHCRNCRWQABU-JTQLQIEISA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

L-Glutamic acid γ-benzyl ester is commonly used in the synthesis of polymers for biological applications. Some of the examples are:
  • Synthesis of bioreducible block copolymers based on poly(ethylene glycol) and poly(γ-benzyl L-glutamate) for Intracellular drug delivery.
  • Synthesis of biodegradable poly(L-glutamic acid)-b-polylactide for magnetic resonance imaging (MRI)-visible drug delivery system.
  • Synthesis of pH and temperature-responsive diblock copolymers based on poly(L-glutamic acid).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN0536
BCCM2876
BCCJ4228
BCCF8691
BCCC0181

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Self-assembly of rod? coil diblock oligomers based on α-helical peptides.
Lecommandoux S, et al.
Macromolecules, 34(26), 9100-9111 (2001)
Bioreducible block copolymers based on poly (ethylene glycol) and poly (γ-benzyl L-glutamate) for intracellular delivery of camptothecin.
Thambi T, et al.
Bioconjugate Chemistry, 22(10), 1924-1931 (2011)
Novel pH?and Temperature?Responsive Block Copolymers with Tunable pH?Responsive Range.
He C, et al.
Macromolecular Rapid Communications, 29(6), 490-497 (2008)
Near-infrared light sensitive polypeptide block copolymer micelles for drug delivery.
Kumar S, et al.
Journal of Materials Chemistry, 22(15), 7252-7257 (2012)
Micelles Based on Biodegradable Poly (l-glutamic acid)-b-Polylactide with Paramagnetic Gd Ions Chelated to the Shell Layer as a Potential Nanoscale MRI? Visible Delivery System.
Zhang G, et al.
Biomacromolecules, 9(1), 36-42 (2007)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service