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49510

L-Glutamic acid γ-benzyl ester

≥99.0% (T)

Synonym(s):

L-Glutamic acid 5-benzyl ester

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About This Item

Linear Formula:
C6H5CH2OCOCH2CH2CH(NH2)COOH
CAS Number:
1676-73-9
Molecular Weight:
237.25
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
57651200
EC Number:
216-826-1
Beilstein/REAXYS Number:
1885646
MDL number:
MFCD00002633
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Quality Segment

100

assay

≥99.0% (T)

optical activity

[α]20/D +19±2°, c = 1% in acetic acid

reaction suitability

reaction type: solution phase peptide synthesis

mp

181-182 °C (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(=O)OCc1ccccc1)C(O)=O

InChI

1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1

InChI key

BGGHCRNCRWQABU-JTQLQIEISA-N

Application

L-Glutamic acid γ-benzyl ester is commonly used in the synthesis of polymers for biological applications. Some of the examples are:
  • Synthesis of bioreducible block copolymers based on poly(ethylene glycol) and poly(γ-benzyl L-glutamate) for Intracellular drug delivery.
  • Synthesis of biodegradable poly(L-glutamic acid)-b-polylactide for magnetic resonance imaging (MRI)-visible drug delivery system.
  • Synthesis of pH and temperature-responsive diblock copolymers based on poly(L-glutamic acid).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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