Key Documents

View All Documentation

529249

2-Chloro-1,3-dimethylimidazolinium chloride

Name: 2-Chloro-1,3-dimethylimidazolinium chloride
Brand: ALDRICH

for peptide synthesis

Synonym(s):

2-Chloro-4,5-dihydro-1,3-dimethyl-1H-imidazolium chloride, DMC

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₅H₁₀Cl₂N₂

CAS Number:

37091-73-9

Molecular Weight:

169.05

UNSPSC Code:

12352005

PubChem Substance ID:

24877665

NACRES:

NA.22

MDL number:

MFCD09039290

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

2-Chloro-1,3-dimethylimidazolinium chloride,

form

crystalline

Quality Level

100

reaction suitability

reaction type: Coupling Reactions

mp

133-140 °C (lit.)

application(s)

peptide synthesis

functional group

chloro

SMILES string

[Cl-].CN1CC[N+](C)=C1Cl

InChI

1S/C5H10ClN2.ClH/c1-7-3-4-8(2)5(7)6;/h3-4H2,1-2H3;1H/q+1;/p-1

InChI key

AEBBXVHGVADBHA-UHFFFAOYSA-M

Description

Application

Activating agent in total synthesis of macroviracin A, cycloviracin B1, and cyclic silanes.

Reagent for synthesis of:
Tagged glucose as an intermediate in the synthesis of branched oligosaccharides
Fluorescent chemosensors
1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1
Allosteric glucokinase activators

Reactant for synthesis of:
Organic azides from primary amines

Reagent for aza-Henry reactions

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Imidazolium-Derived Reagents

N-Acylimidazoles and carbonylimidazoles are reactive intermediates used for amino compound acylation, surpassing DCC as coupling reagents.

Synthetic studies on macroviracin A: a rapid construction of C(42) macrocyclic dilactone corresponding to the core.

Shunya Takahashi et al.

The Journal of organic chemistry, 69(13), 4509-4515 (2004-06-19)

The C(2)-symmetric macrodiolide core 2 of an antiviral agent, macroviracin A (1), was constructed in a single step by the intermolecular macrodimerization of C(22)-hydroxy carboxylic acid 3 with 2-chloro-1,3-dimethylimidazolinium chloride and DMAP in the presence of sodium hydride (NaH). The

Structure assignment, total synthesis, and antiviral evaluation of cycloviracin B1.

Alois Fürstner et al.

Journal of the American Chemical Society, 125(43), 13132-13142 (2003-10-23)

The first total synthesis of the antivirally active glycolipid cycloviracin B(1) (1) is described. The approach is based on a two-directional synthesis strategy which constructs the C(2)()-symmetrical macrodiolide core of the target by an efficient template-directed macrodilactonization reaction promoted by

Journal of Organometallic Chemistry, 686, 175-182 (2003)

View All Related Papers

Global Trade Item Number

SKU	GTIN
529249-100G	04061833548158
529249-5G	04061832557977
529249-25G	04061832557960