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About This Item
Linear Formula:
HS(CH2)6SH
CAS Number:
Molecular Weight:
150.31
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
214-735-1
Beilstein/REAXYS Number:
1732507
MDL number:
InChI key
SRZXCOWFGPICGA-UHFFFAOYSA-N
InChI
1S/C6H14S2/c7-5-3-1-2-4-6-8/h7-8H,1-6H2
SMILES string
SCCCCCCS
vapor pressure
~1 mmHg ( 20 °C)
assay
99.5%
form
liquid
refractive index
n20/D 1.511 (lit.)
bp
118-119 °C/15 mmHg (lit.)
mp
−21 °C (lit.)
density
0.983 g/mL at 25 °C (lit.)
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General description
1,6-Hexanedithiol (HDT) is a long chained bi-functional alkanethiol with 6 carbon atoms structured in a zig-zag pattern, which forms a tetrahedral configuration. It forms a self-assembled monolayer (SAM) on a variety of substrates and immobilizes the surface atoms.
Application
HDT forms a SAM on Au, Pt, and Ag substrates, which can be used as coated electrode materials for electrochemical and biological detections. These electrodes form a sensing platform that can be used in biomedical and biosensing applications.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
195.8 °F - closed cup
flash_point_c
91 °C - closed cup
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Nucleic acid-functionalized Pt nanoparticles: catalytic labels for the amplified electrochemical detection of biomolecules
Polsky R, et al.
Analytical Chemistry, 78(7), 2268-2271 (2006)
Length-dependent transport in molecular junctions based on SAMs of alkanethiols and alkanedithiols: effect of metal work function and applied bias on tunneling efficiency and contact resistance
Engelkes VB, et al.
Journal of the American Chemical Society, 126(43), 14287-14296 (2004)
Covalent attachment of glucose oxidase to an Au electrode modified with gold nanoparticles for use as glucose biosensor
Zhang S, et al.
Bioelectrochemistry, 67(1), 15-22 (2005)
Combined TPD and XPS Study of Ligation and Decomposition of 1, 6-Hexanedithiol on Size-Selected Copper Clusters Supported on HOPG.
Wang L, et al.
The Journal of Physical Chemistry C, 122(4), 2173-2183 (2018)
A regenerating self-assembled gold nanoparticle-containing electrochemical impedance sensor.
Mahmoud AM, et al.
Biosensors And Bioelectronics, 56(2), 328-333 (2014)
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