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Merck
CN

725382

1,6-Hexanedithiol

99.5%

Synonym(s):

1,6-Dimercaptohexane, DMH, Hexamethylene dimercaptan

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About This Item

Linear Formula:
HS(CH2)6SH
CAS Number:
Molecular Weight:
150.31
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
214-735-1
Beilstein/REAXYS Number:
1732507
MDL number:
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InChI key

SRZXCOWFGPICGA-UHFFFAOYSA-N

InChI

1S/C6H14S2/c7-5-3-1-2-4-6-8/h7-8H,1-6H2

SMILES string

SCCCCCCS

vapor pressure

~1 mmHg ( 20 °C)

assay

99.5%

form

liquid

refractive index

n20/D 1.511 (lit.)

bp

118-119 °C/15 mmHg (lit.)

mp

−21 °C (lit.)

density

0.983 g/mL at 25 °C (lit.)

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General description

1,6-Hexanedithiol (HDT) is a long chained bi-functional alkanethiol with 6 carbon atoms structured in a zig-zag pattern, which forms a tetrahedral configuration. It forms a self-assembled monolayer (SAM) on a variety of substrates and immobilizes the surface atoms.

Application

HDT forms a SAM on Au, Pt, and Ag substrates, which can be used as coated electrode materials for electrochemical and biological detections. These electrodes form a sensing platform that can be used in biomedical and biosensing applications.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

195.8 °F - closed cup

flash_point_c

91 °C - closed cup


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Nucleic acid-functionalized Pt nanoparticles: catalytic labels for the amplified electrochemical detection of biomolecules
Polsky R, et al.
Analytical Chemistry, 78(7), 2268-2271 (2006)
Length-dependent transport in molecular junctions based on SAMs of alkanethiols and alkanedithiols: effect of metal work function and applied bias on tunneling efficiency and contact resistance
Engelkes VB, et al.
Journal of the American Chemical Society, 126(43), 14287-14296 (2004)
Covalent attachment of glucose oxidase to an Au electrode modified with gold nanoparticles for use as glucose biosensor
Zhang S, et al.
Bioelectrochemistry, 67(1), 15-22 (2005)
Combined TPD and XPS Study of Ligation and Decomposition of 1, 6-Hexanedithiol on Size-Selected Copper Clusters Supported on HOPG.
Wang L, et al.
The Journal of Physical Chemistry C, 122(4), 2173-2183 (2018)
A regenerating self-assembled gold nanoparticle-containing electrochemical impedance sensor.
Mahmoud AM, et al.
Biosensors And Bioelectronics, 56(2), 328-333 (2014)

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