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Merck
CN

727997

Fmoc-Cys(4-methoxytrityl)-OH

≥98% (HPLC), for peptide synthesis

Synonym(s):

(R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[(4-methoxyphenyl)diphenylmethylsulfanyl]propionic acid, Fmoc-Cys(Mmt)-OH, Nα-(9-Fluorenylmethyloxycarbonyl)-S-4-methoxytrityl-L-cysteine

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About This Item

Empirical Formula (Hill Notation):
C38H33NO5S
CAS Number:
177582-21-7
Molecular Weight:
615.74
NACRES:
NA.26
PubChem Substance ID:
329764368
UNSPSC Code:
12352209
MDL number:
MFCD00270541
Beilstein/REAXYS Number:
8524562

Key Documents

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Product Name

Fmoc-Cys(4-methoxytrityl)-OH, ≥98% (HPLC)

InChI key

LOBUWFUSGOYXQX-DHUJRADRSA-N

InChI

1S/C38H33NO5S/c1-43-29-22-20-28(21-23-29)38(26-12-4-2-5-13-26,27-14-6-3-7-15-27)45-25-35(36(40)41)39-37(42)44-24-34-32-18-10-8-16-30(32)31-17-9-11-19-33(31)34/h2-23,34-35H,24-25H2,1H3,(H,39,42)(H,40,41)/t35-/m0/s1

SMILES string

COc1ccc(cc1)C(SC[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)(c5ccccc5)c6ccccc6

assay

≥98% (HPLC)

form

lumps

optical activity

[α]/D +14.0±1.0°, c = 1 in THF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

Quality Level

100

Related Categories

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM5843
BCCJ7348
BCCG3275
BCBZ3704
BCBW4059

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Elyse T Williams et al.
Angewandte Chemie (International ed. in English), 57(36), 11640-11643 (2018-07-07)
We report a new method herein coined SP-CLipPA (solid-phase cysteine lipidation of a peptide or amino acid) for the synthesis of mono-S-lipidated peptides. This technique utilizes thiol-ene chemistry for conjugation of a vinyl ester to a free thiol of a

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