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765449

Gold nanoparticles

5 nm diameter, carboxylic acid functionalized, PEG 5000 coated, dispersion in H2O

Synonym(s):

Gold nanoparticles COOH functionalized, Au NP COOH, Gold Colloid

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About This Item

UNSPSC Code:
12352302
NACRES:
NA.23
PubChem Substance ID:
329767174
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material

PEG 5000

form

dispersion in H2O, nanoparticles

packaging

glass bottle of 1 mL

OD

50

diameter

5 nm

pH

6.0-8.0 (25 °C)

solubility

water: miscible

density

1.00 g/cm3

λmax

515 nm

functional group

carboxylic acid

storage temp.

2-8°C

Application

Carboxylic acid functionalized, PEG 5000 coated and H2O dispersed gold nanoparticles (5 nm) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may be used to prepare SARS-CoV-2 conjugate for COVID-19 detection using lateral flow immunoassay technique. It may also be used in immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Features and Benefits

Decreases the cytotoxicity and increases efficiency of GNPs in targeted drug delivery. PEG increases the stability of the nanoparticles and prevents agglomeration.

Other Notes

  • form dispersion in H2O
  • OD 50
  • diameter 5 nm
  • storage temp. 2-8°C

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP5533
MKCM1689
MKCJ8150
MKCH8735
MKBN9273V

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Articles

Magnetic Nanoparticles for Cancer Theranostics

The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.

Micro- and Nanofabricated Biomaterials

Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.

用于癌症诊断治疗的磁性纳米颗粒

最近出现的许多高功能纳米材料为癌症的认识、诊断和治疗提供了新的方案。

Jennifer Mytych et al.
BioMed research international, 2015, 304575-304575 (2015-07-23)
Nanogold-based materials are promising candidate tools for nanobased medicine. Nevertheless, no conclusive information on their cytotoxicity is available. In the present study, we investigated the effects of gold nanoparticles (AuNPs) on human astrocytes in vitro. Nanogold treatment in a wide
Alexandre Albanese et al.
ACS nano, 5(7), 5478-5489 (2011-06-23)
Aggregation appears to be a ubiquitous phenomenon among all nanoparticles and its influence in mediating cellular uptake and interactions remain unclear. Here we developed a simple technique to produce transferrin-coated gold nanoparticle aggregates of different sizes and characterized their uptake
Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
Li Z, et al.
Journal of Medical Virology, 6, 2071-2071 (2020)
View All Related Papers

Global Trade Item Number

SKUGTIN
765449-1ML04061837524073