Skip to Content
Merck
CN

Key Documents

View All Documentation

773069

Fmoc-N-Me-Cys(Trt)-OH

97% (HPLC)

Synonym(s):

N-α-Fmoc-N-α-methyl-S-trityl-L-cysteine

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C38H33NO4S
CAS Number:
944797-51-7
Molecular Weight:
599.74
MDL number:
MFCD11973909
UNSPSC Code:
12352209
NACRES:
NA.26
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Segment

assay

97% (HPLC)

form

powder or crystals

optical activity

[α]22/D -25.0°, c = 0.5% in dichloromethane

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

234-239 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

S(C[C@H](N(C)C(=O)OCC4c5c(cccc5)c6c4cccc6)C(=O)O)C(c3ccccc3)(c2ccccc2)c1ccccc1

InChI

1S/C38H33NO4S/c1-39(37(42)43-25-34-32-23-13-11-21-30(32)31-22-12-14-24-33(31)34)35(36(40)41)26-44-38(27-15-5-2-6-16-27,28-17-7-3-8-18-28)29-19-9-4-10-20-29/h2-24,34-35H,25-26H2,1H3,(H,40,41)/t35-/m0/s1

InChI key

RAKOPMQMPUNRGI-DHUJRADRSA-N

Application

Fmoc-N-Me-Cys(Trt)-OH is a Fmoc-protected derivative of N-methyl cysteine used as a building block to prepare peptide thioesters under acidic conditions. The residue attached to the amino group of N-methylcysteine can migrate to the cysteinyl thiol group, resulting in the formation of a peptide thioester. The introduction of this Fmoc-protected derivative is best achieved using HATU as a coupling reagent in the presence of DIPEA (N, N-Diisopropylethylamine).
It can also be used to prepare Fmoc-N-Me-Cys(Trt)-OAllyl intermediate for the solid-phase synthesis of dithiol Triostin A.

Still not finding the right product?

Explore all of our products under Fmoc-N-Me-Cys(Trt)-OH

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library