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Merck
CN

900743

Branched PEI-g-PEG

PEG Mn 5,000

Synonym(s):

Branched polyethylenimine-graft-poly(ethylene glycol), PEI-g-PEG, PEI-PEG

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About This Item

Linear Formula:
H3CO(CH2CH2O)nC10H18N2O3(NHCH2CH2)mNH2
NACRES:
NA.23
UNSPSC Code:
12162002
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form

liquid

Quality Level

mol wt

PEG Mn 5,000

storage temp.

2-8°C

Application

Branched PEI-g-PEG, PEG Mn 5000 was derived from Sigma-Aldrich Product 408727. Based upon an approximate Mw of 25,000 for the branched PEI, Product 900926 contains approximately 15 grafted PEG chains per PEI unit (by NMR).


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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

CRISPR/Cas9 delivery via nonviral nanoparticles shows promising advancements for gene editing in disease treatment.


Katharina Ladewig et al.
Journal of biomedical materials research. Part A, 102(7), 2137-2146 (2013-07-31)
High molecular weight (MW) polyethyleneimine (PEI) has been successfully used for the transfection of a broad variety of cell lines. In contrast to low MW PEI, which exhibits low transfection efficiencies but also low cytotoxicity, high MW PEI-mediated transfection achieves
Chunxi Liu et al.
Biomaterials, 34(10), 2547-2564 (2013-01-22)
Co-delivery of nucleic acids and chemotherapeutics has a potential to efficaciously treat human diseases via their synergetic effects. Activable therapeutic tools at the nanoscale are suitable platforms for combination therapy. In this study, we have developed a multifunctional nanoscaled delivery
Jing Wang et al.
Biomaterials science, 4(9), 1351-1360 (2016-07-19)
Zwitterionic poly(carboxybetaine) (PCB), poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) and non-ionic poly(ethylene glycol) (PEG), which have similar degrees of polymerization, were grafted to branched polyethyleneimine (PEI) to generate PCB-grafted PEI (PEI-PCB), PMPC-grafted PEI (PEI-PMPC) and PEG-grafted PEI (PEI-PEG) copolymers, respectively. These grafted PEI



Global Trade Item Number

SKUGTIN
900743-1G04061824070743