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901594

Diisopropylcarbodiimide solution

1 M in THF

Synonym(s):

Diisopropylmethanediimine

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About This Item

Linear Formula:
C7H14N2
CAS Number:
693-13-0
UNSPSC Code:
12352111
NACRES:
NA.22
MDL number:
MFCD00065689
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form

liquid

reaction suitability

reaction type: Coupling Reactions

concentration

1 M in THF

density

0.870 g/mL

application(s)

peptide synthesis

SMILES string

N(=C=NC(C)C)C(C)C

InChI

1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3

InChI key

BDNKZNFMNDZQMI-UHFFFAOYSA-N

Application

Coupling reagent for peptide syntheses.
DIC (N,N′-Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N-allylglycine to form N-allylpeptide.
Valuable reagent offered as a solution in tetrahydrofuran for more convenient handling.

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Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Resp. Sens. 1 - Skin Sens. 1 - STOT SE 3

supp_hazards

EUH019

Storage Class

3 - Flammable liquids

flash_point_f

2.0 °F

flash_point_c

-16.66 °C

target_organs

Central nervous system, Respiratory system

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