914924
3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid
≥95%
Synonym(s):
3-((2-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)disulfaneyl)propanoic acid, Biotin-SS-COOH, Cleavable biotin linker
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About This Item
Empirical Formula (Hill Notation):
C15H25N3O4S3
CAS Number:
Molecular Weight:
407.57
UNSPSC Code:
12352106
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
powder
Quality Level
assay
≥95%
form
powder
mp
172-175 °C
storage temp.
−20°C
SMILES string
S1[C@H]([C@H]2NC(=O)N[C@H]2C1)CCCCC(=O)NCCSSCCC(=O)O
InChI
1S/C15H25N3O4S3/c19-12(16-6-8-25-24-7-5-13(20)21)4-2-1-3-11-14-10(9-23-11)17-15(22)18-14/h10-11,14H,1-9H2,(H,16,19)(H,20,21)(H2,17,18,22)/t10-,11-,14-/m0/s1
InChI key
LUKYYZVIDAWYMZ-MJVIPROJSA-N
Application
3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid (Biotin-SS-COOH) is a cleavable, biotinylated crosslinkers. The linker can also be used for synthesis of chemical biology tools for labeling target proteins in biological experiments and assays. It possesses dual functionality: enrichment via the biotin and an embedded disulfide bridge for cleavage under reducing conditions.
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Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)
Other Notes
Uniformly Cationized Protein Efficiently Reaches the Cytosol of Mammalian Cells
A Mechanism-Based ICAT Strategy for Comparing Relative Expression and Activity Levels of Glycosidases in Biological Systems
Dissociation-independent selection of high-affinity anti-hapten phage antibodies using cleavable biotin-conjugated haptens
A Mechanism-Based ICAT Strategy for Comparing Relative Expression and Activity Levels of Glycosidases in Biological Systems
Dissociation-independent selection of high-affinity anti-hapten phage antibodies using cleavable biotin-conjugated haptens
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 914924-50MG | 04061842083893 |