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934798

Gelatin acrylate

gel strength 300 g Bloom, degree of substitution 60%

Synonym(s):

Gelatin acrylate, Acrylated gelatin, Gelatin / GelMA & derivatives

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About This Item

Linear Formula:
(C40H59N11O13)n
NACRES:
NA.21
UNSPSC Code:
12352202
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Quality Level

100

form

powder or chunks (fibers)

color

white to off-white

storage temp.

−20°C

General description

Gelatin is a natural biopolymer derived from collagen that plays an important role in the biomedical field due to its biocompatibility, biodegradability, and nonimmunogenicity. Acrylate-functionalized gelatin, or gelatin acrylate, can be crosslinked using thiol-Michael click chemistry as well as photochemical crosslinking. It′s properties are very similar to gelatin methacrylate (GelMA). Crosslinked gelatin hydrogels have many applications in tissue engineering and 3D bioprinting.

Application

  • Endothelial cell morphogenesis
  • Injectable tissue constructs
  • Tissue engineering of multiple tissue types including heart tissue (cardiomyocytes), bone tissue (osteogenesis), cartilage tissue (chondrogenesis), and epidermal tissue
  • Drug delivery applications including contact lens and dental

Features and Benefits

  • Photopolymerizable
  • Clickable
  • Biocompatible
  • Biodegradable

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT9278

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Hongyuan Zhu et al.
Journal of the mechanical behavior of biomedical materials, 88, 160-169 (2018-09-03)
Biocompatible hydrogels with defined mechanical properties are critical to tissue engineering and regenerative medicine. Thiol-acrylate photopolymerized hydrogels have attracted special interest for their degradability and cytocompatibility, and for their tunable mechanical properties through controlling factors that affect reaction kinetics (e.g.
Xin Zhao et al.
Advanced healthcare materials, 5(1), 108-118 (2015-04-17)
Natural hydrogels are promising scaffolds to engineer epidermis. Currently, natural hydrogels used to support epidermal regeneration are mainly collagen- or gelatin-based, which mimic the natural dermal extracellular matrix but often suffer from insufficient and uncontrollable mechanical and degradation properties. In
Chaenyung Cha et al.
Biomacromolecules, 15(1), 283-290 (2013-12-19)
Microfabrication technology provides a highly versatile platform for engineering hydrogels used in biomedical applications with high-resolution control and injectability. Herein, we present a strategy of microfluidics-assisted fabrication photo-cross-linkable gelatin microgels, coupled with providing protective silica hydrogel layer on the microgel
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Global Trade Item Number

SKUGTIN
934798-1G04065270326997
934798-5G04065270327277