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Merck
CN

G-005

Glutethimide solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C13H15NO2
CAS Number:
Molecular Weight:
217.26
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6
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InChI key

JMBQKKAJIKAWKF-UHFFFAOYSA-N

InChI

1S/C13H15NO2/c1-2-13(10-6-4-3-5-7-10)9-8-11(15)14-12(13)16/h3-7H,2,8-9H2,1H3,(H,14,15,16)

SMILES string

CCC1(CCC(=O)NC1=O)c2ccccc2

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal), kontrollierte Droge in Deutschland

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

General description

Glutethimide is a hypnotic sedative sold under the trade name Doriden. Glutethimide has a history of abuse in combination with codeine. This Certified Snap-N-Spike® Solution is applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from urine drug testing to forensic analysis and clinical toxicology.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

监管及禁止进口产品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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H Y Aboul-Enein et al.
Die Pharmazie, 59(11), 833-835 (2004-12-14)
The enantiomeric resolution of p-acetylaminoglutethimide and p-nitroglutethimide was achieved on a Ceramospher RU-2 column using methanol as the mobile phase. The flow rates of the mobile phase were 1.0 and 0.5 mL/min for p-acetylaminoglutethimide and p-nitroglutethimide, respectively, with UV detection
Wojciech Mańkowski et al.
Przeglad lekarski, 59(4-5), 390-391 (2002-08-20)
Suicidal attempt with old (currently unused) drug is described. The suicidal attempts are usually performed with the use of contemporary pharmacotherapeutics. In the report a case of suicidal attempt with old drug Tardyl is presented. Tardyl (Glutethimid) was prescribed to
E E Cable et al.
European journal of biochemistry, 240(1), 112-117 (1996-08-15)
Hepatic 5-aminolevulinic acid synthase, the first and normally rate-controlling enzyme of heme biosynthesis, is regulated by heme. One of the known mechanisms whereby increased cellular heme regulates 5-aminolevulinic acid synthase is by decreasing the stability of its mRNA. In primary
Marie-Josée Rocheleau
Electrophoresis, 26(12), 2320-2329 (2005-05-25)
Generic capillary electrophoresis (CE) conditions have been implemented for chiral separations in early pharmaceutical development. The chiral CE separations of several pharmaceutical samples at different stages of development, i.e., discovery, process chemistry, and investigative new drug application, have been obtained
Sridevi Kolluri et al.
The Biochemical journal, 392(Pt 1), 173-180 (2005-07-22)
Haem is essential for the health and function of nearly all cells. 5-Aminolaevulinic acid synthase-1 (ALAS-1) catalyses the first and rate-controlling step of haem biosynthesis. ALAS-1 is repressed by haem and is induced strongly by lipophilic drugs that also induce

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