CBL1512F
Anti-Integrin αM [CD11b] Antibody, clone OX-42, FITC conjugated
clone OX-42, Chemicon®, from mouse
Synonym(s):
CD11b
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
FITC conjugate
Clone:
OX-42, monoclonal
Application:
FACS, IHC
Citations:
5
biological source
mouse
Quality Segment
conjugate
FITC conjugate
antibody product type
primary antibodies
clone
OX-42, monoclonal
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable, immunohistochemistry: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
rat ... Itgam(25021)
Application
Flow cytometry
Immunohistochemical studies of rat fresh frozen tissue sections following either periodate-lysine-paraformaldehyde (PLP) fixation, or acetone. Works on very lightly PFA fixed, frozen tissues. (perfusion only 4% PFA 10-15′ no post-fix).
Optimal working dilutions must be determined by the end user.
Immunohistochemical studies of rat fresh frozen tissue sections following either periodate-lysine-paraformaldehyde (PLP) fixation, or acetone. Works on very lightly PFA fixed, frozen tissues. (perfusion only 4% PFA 10-15′ no post-fix).
Optimal working dilutions must be determined by the end user.
This Anti-Integrin αM CD11b Antibody, clone OX-42, FITC conjugated is validated for use in FC, IH for the detection of Integrin αM [CD11b].
Biochem/physiol Actions
This antibody recognizes most macrophages (including resident peritoneal and activated macrophages), kupffer cells, but only about 35% of alveolar macrophages. The antibody also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain. The antibody precipitates three polypeptides of 150, 103 and 95 KDa. The antibody inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for IC3b called CR3.
FUSION PARTNER: NSO myeloma cell line.
FUSION PARTNER: NSO myeloma cell line.
Other Notes
Replaces: MAB1404F
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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