MAB2146Z
Anti-ICAM-1 Antibody, clone P2A4, Azide Free
clone P2A4, Chemicon®, from mouse
Synonym(s):
CD54, MAB2146
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
P2A4, monoclonal
Application:
ELISA, FACS, ICC, IHC, IP
Citations:
7
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
P2A4, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... ICAM1(3383)
Immunogen
IL-1beta activated HUVEC (human)
Application
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue
Immunocytochemistry: for use on B cells, PBL, T cells
Immunoprecipitation
FACS
ELISA
Inhibits ICAM-1 dependent adhesive interactions
Optimal working dilutions must be determined by end user.
Immunocytochemistry: for use on B cells, PBL, T cells
Immunoprecipitation
FACS
ELISA
Inhibits ICAM-1 dependent adhesive interactions
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
This Anti-ICAM-1 Antibody, clone P2A4, Azide Free is validated for use in ELISA, FC, IP, IC, IH, FUNC for the detection of ICAM-1.
Biochem/physiol Actions
Human ICAM-1
Physical form
Format: Purified
Sterile-filtered lquid containing 0.2M phosphate buffer, 0.25M sodium chloride, no preservatives.
Preparation Note
Maintain at -20°C.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro.
Ghislin, S; Obino, D; Middendorp, S; Boggetto, N; Alcaide-Loridan, C; Deshayes, F
BMC Cancer null
Kelly M Bailey et al.
Oncotarget, 10(36), 3385-3399 (2019-06-06)
Metastatic and relapsed Ewing sarcoma typically afflicts the adolescent population and is largely fatal. These bone tumors are most commonly driven by the fusion oncoprotein EWS-FLI1. Ewing tumors demonstrate significant intra-tumoral heterogeneity, and individual tumor cells can express highly variable
Mario C Manresa et al.
Gastroenterology, 159(5), 1778-1792 (2020-07-28)
Eosinophilic esophagitis (EoE) is an antigen-mediated eosinophilic disease of the esophagus that involves fibroblast activation and progression to fibrostenosis. Cytokines produced by T-helper type 2 cells and transforming growth factor beta 1 (TGFβ1) contribute to the development of EoE, but
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB2146Z | 04053252661990 |