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Merck
CN

MABE1874

Sigma-Aldrich

Anti-RING2/RNF2 Antibody, Clone 3-3

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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conjugate

unconjugated

antibody form

purified antibody

clone

3-3
monoclonal

purified by

using protein G

species reactivity

mouse, human, human, monkey, mouse, monkey, mouse

concentration

(Please refer to lot specific datasheet.)

technique(s)

ChIP: suitable
immunocytochemistry: suitable
western blot: suitable

isotype

IgG2bκ

UniProt accession no.

target post-translational modification

unmodified

General description

GST-tagged full length murine RING2 protein.
~42 kDa observed; 37.62 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Application

Immunoprecipitation Analysis: A representative lot immunoprecipitated RING2/RNF2 in Immunoprecipitation applications (Yakushiji-Kaminatsui, N., et. al. (2016). Development. 143(2):276-85; Atsuta, T., et. al. (2001). Hybridoma. 20(1):43-6; Endoh, M., et. al. (2017). Elife. 6. pii: e27970).

Immunocytochemistry Analysis: A representative lot detected RING2/RNF2 in Immunocytochemistry applications (Atsuta, T., et. al. (2001). Hybridoma. 20(1):43-6).

Chromatin Immunoprecipitation Analysis (ChIP): A representative lot detected RING2/RNF2 in Chromatin Immunoprecipitation applications (Farcas, A.M., et. al. (2012). Elife. 1:e00205; Endoh, M., et. al. (2017). Elife. 6. pii: e27970).

Western Blotting Analysis: A representative lot detected RING2/RNF2 in Western Blotting applications (Atsuta, T., et. al. (2001). Hybridoma. 20(1):43-6).

Biochem/physiol Actions

Clone 3-3 is a mouse monoclonal antibody that specifically detects E3 ubiquitin-protein ligase RING2 (RING1B).

Physical form

Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in U20S cell lysates.

Western Blotting Analysis: 1 µg/mL of this antibody detected RING2/RNF2 in U20S cell lysate.

Other Notes

Human, Monkey, Mouse.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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