01-3540
6-Aminocaproic acid
SAJ special grade, ≥99.0%
Synonym(s):
ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA
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About This Item
Linear Formula:
H2N(CH2)5CO2H
CAS Number:
Molecular Weight:
131.17
EC Number:
200-469-3
UNSPSC Code:
12352116
PubChem Substance ID:
Beilstein/REAXYS Number:
906872
MDL number:
grade
SAJ special grade
assay
≥99.0%
form
solid
availability
available only in Japan
mp
207 °C, 207-209 °C (dec.) (lit.)
solubility
water: soluble
application(s)
peptide synthesis
SMILES string
NCCCCCC(O)=O
InChI
1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI key
SLXKOJJOQWFEFD-UHFFFAOYSA-N
Gene Information
human ... PLAT(5327), PLG(5340)
Biochem/physiol Actions
Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis.
Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.
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Storage Class
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
flash_point_f
404.6 - 408.2 °F
flash_point_c
207 - 209 °C
Regulatory Information
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Moumita Ghosh et al.
Langmuir : the ACS journal of surfaces and colloids, 28(3), 1715-1724 (2011-12-29)
The present work reports covalent functionalization of single-walled carbon nanotubes (f-SWNTs) to introduce hydrophilicity to the otherwise amphiphobic nanotubes. The charge and spacer length of the functional moiety were varied by using quaternized ethylene diamine, 6-aminocaproate, quaternized (ethylenedioxy)bis(ethylamine), and a
E M Van Hoeyveld et al.
The Journal of allergy and clinical immunology, 76(4), 543-550 (1985-10-01)
The effect of epsilon-aminocaproic acid (EACA) on the degradation of an aqueous Lolium perenne extract was studied by intracutaneous tests and by RAST inhibition. Extracts for skin testing stored at 4 degrees C for 12 months and at 37 degrees
P A Stricker et al.
British journal of anaesthesia, 110(5), 788-799 (2013-01-29)
Understanding the clinical pharmacology of the antifibrinolytic epsilon-aminocaproic acid (EACA) is necessary for rational drug administration in children. The aim of this study is to determine the pharmacokinetics (PKs) of EACA in infants aged 6-24 months undergoing craniofacial reconstruction surgery.