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Merck
CN

00370580

Ginsenoside Rg1

primary reference standard

Synonym(s):

(3β,6α,12β)-3,12-Dihydroxydammar-24-ene-6,20-diyl bis-β-D-glucopyranoside, Ginsenoside A2, Ginsenoside g1, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1

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About This Item

Empirical Formula (Hill Notation):
C42H72O14
CAS Number:
22427-39-0
Molecular Weight:
801.01
NACRES:
NA.24
PubChem Substance ID:
329747051
UNSPSC Code:
85151701
EC Number:
244-989-9
MDL number:
MFCD00210293

Key Documents

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Product Name

Ginsenoside Rg1, primary reference standard

InChI key

YURJSTAIMNSZAE-HHNZYBFYSA-N

InChI

1S/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1

SMILES string

C[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@@](CCC=C(C)C)(C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C)O)([H])[C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])[C@H](C1)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)C

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

shipped in

dry ice

storage temp.

−20°C

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Application

Reference standard in the analysis of herbal medicinal products.

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Other Notes

This compound is commonly found in plants of the genus: panax

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
HWI03094-1
HWI03094
HWI02086-2
HWI02086-1
HWI02086

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Jiaying Wu et al.
Neuropharmacology, 63(3), 349-361 (2012-04-27)
Ginsenoside Rg1 (Rg1) acts as a neuroprotective agent against various insults, however, the underlying mechanism has not been fully elucidated yet. Here, we report that Rg1 protects primary rat cerebrocortical neurons against β-amyloid peptide₂₅₋₃₅ (Aβ₂₅₋₃₅) injury via estrogen receptor α
Constance Lay Lay Saw et al.
Chemical research in toxicology, 25(8), 1574-1580 (2012-07-12)
Ginseng has long been used in Asian countries for more than 2000 years. Currently, in the "Western World or Western Medicines", many reports have indicated that they have used herbal medicines, and ginseng is one of the most popular herbs.
Fang Chen et al.
Biological & pharmaceutical bulletin, 35(9), 1568-1573 (2012-09-15)
Apoptosis is the main form of β-cell death in diabetes. Ginseng has been used as an anti-diabetic herb for several thousand years in Asia with ginsenoside Rg1 and ginsenoside Rb1 as important active ingredients. In this study, we demonstrated ginsenoside
Wen-Fang Chen et al.
Menopause (New York, N.Y.), 19(9), 1052-1061 (2012-05-03)
The present study was designed to determine whether ginsenoside Rg1 could exert selective estrogenic effects by using both cell lines and an animal model. The endometrial Ishikawa cells and preosteoblastic MC3T3-E1 cells were treated with a different dose of Rg1.
Shang-Fu Xu et al.
European journal of pharmacology, 695(1-3), 7-12 (2012-09-04)
This study was aimed to investigate the effects of ginsenoside Rg1 (Rg1) on hematopoietic function of bone marrow in cyclophosphamide-induced bone marrow depression mice. Mice were given cyclophosphamide (150mg/kg, i.p. for three days) to produce bone marrow depression. Rg1 was
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