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Merck
CN

03880590

Luteolin

primary reference standard

Synonym(s):

3′,4′,5,7-Tetrahydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
491-70-3
Molecular Weight:
286.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329747828
EC Number:
207-741-0
Beilstein/REAXYS Number:
292084
MDL number:
MFCD00017309

Key Documents

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Product Name

Luteolin, primary reference standard

InChI key

IQPNAANSBPBGFQ-UHFFFAOYSA-N

InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

mp

~330 °C (lit.)

application(s)

food and beverages

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Application

Reference Standard in the analysis of herbal medicinal products

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Other Notes

This compound is commonly found in plants of the genus: achillea

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
HWI03169-1
HWI03169
HWI02485-1
HWI02485
HWI02293

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Theoharis C Theoharides et al.
Advances in experimental medicine and biology, 601, 423-430 (2007-08-24)
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) mainly mediated by Th1, but recent evidence indicates that Th2 T cells, mostly associated with allergic reactions, are also involved. Mast cells are involved in allergic and
Yong Lin et al.
Current cancer drug targets, 8(7), 634-646 (2008-11-11)
Luteolin, 3',4',5,7-tetrahydroxyflavone, is a common flavonoid that exists in many types of plants including fruits, vegetables, and medicinal herbs. Plants rich in luteolin have been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and
Lien Verschooten et al.
PloS one, 7(10), e48264-e48264 (2012-10-31)
Flavonoids are widely proposed as very interesting compounds with possible chemopreventive and therapeutic capacities. In this study, we showed that in vitro treatment with the flavonoid Luteolin induced caspase-dependent cell death in a model of human cutaneous squamous cell carcinoma
Günter Seelinger et al.
Planta medica, 74(14), 1667-1677 (2008-10-22)
Luteolin is a flavone which occurs in medicinal plants as well as in some vegetables and spices. It is a natural anti-oxidant with less pro-oxidant potential than the flavonol quercetin, the best studied flavonoid, but apparently with a better safety
Leticia Correa Manjolin et al.
Food chemistry, 141(3), 2253-2262 (2013-07-23)
Fisetin, quercetin, luteolin and 7,8-hydroxyflavone show high activity in Leishmania cultures and present low toxicity to mammalian cells. In this work, the structural aspects of 13 flavonoids were analyzed for their inhibition of the arginase enzyme from Leishmania (Leishmania) amazonensis.
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