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Merck
CN

06279

Mangiferin

analytical standard

Synonym(s):

1,3,6,7-Tetrahydroxyxanthone C2-β-D-glucoside, Chinomin, Chinonin, Shamimin

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About This Item

Empirical Formula (Hill Notation):
C19H18O11
CAS Number:
Molecular Weight:
422.34
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
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grade

analytical standard

Quality Level

assay

≥98.0% (TLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3Oc4cc(O)c(O)cc4C(=O)c3c2O

InChI

1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1

InChI key

AEDDIBAIWPIIBD-ZJKJAXBQSA-N

General description

Mangiferin is a xanthone glucoside and a naturally occurring polyphenol found abundantly in the plants of genus Mangifera particularly Mangifera indica L. and also in some medicinal herbs. Mangiferin exhibits antioxidant, antiviral, antitumor, anti-inflammatory and gene-regulatory effects and is considered to be of high research interest due to its therapeutic properties.

Application

Mangiferin may be used as an analytical standard for the determination of the analyte in rat plasma, traditional Chinese medicines and honeybush tea (Cyclopia spp.) by chromatography based techniques.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: hypericum


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pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Reversed-phase HPLC determination of mangiferin, isomangiferin and hesperidin in Cyclopia and the effect of harvesting date on the phenolic composition of C. genistoides
Joubert E, et al.
European Food Research and Technology, 216(3), 270-273 (2003)
Dandan Han et al.
Journal of pharmaceutical and biomedical analysis, 51(1), 260-263 (2009-08-25)
An ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method employing electrospray ionization (ESI) has been developed for the determination of mangiferin in rat plasma using diphenhydramine as the internal standard (IS). Liquid-liquid extraction (LLE) was used for sample preparation and
High-performance liquid chromatographic method for the determination of mangiferin, likviritin and dihydroquercetin in rat plasma and urine
Geodakyan SV, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 577(2), 371-375 (1992)



Global Trade Item Number

SKUGTIN
128740-25G04061832544588
128740-5G04061832544595
06279-10MG04061838646019