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Merck
CN

06279

Mangiferin

analytical standard

Synonym(s):

1,3,6,7-Tetrahydroxyxanthone C2-β-D-glucoside, Chinomin, Chinonin, Shamimin

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About This Item

Empirical Formula (Hill Notation):
C19H18O11
CAS Number:
4773-96-0
Molecular Weight:
422.34
NACRES:
NA.24
PubChem Substance ID:
329748228
UNSPSC Code:
85151701
MDL number:
MFCD00075656

Key Documents

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Product Name

Mangiferin, analytical standard

InChI

1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc3Oc4cc(O)c(O)cc4C(=O)c3c2O

InChI key

AEDDIBAIWPIIBD-ZJKJAXBQSA-N

grade

analytical standard

assay

≥98.0% (TLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

100

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Other Notes

This compound is commonly found in plants of the genus: hypericum

Application

Mangiferin may be used as an analytical standard for the determination of the analyte in rat plasma, traditional Chinese medicines and honeybush tea (Cyclopia spp.) by chromatography based techniques.

General description

Mangiferin is a xanthone glucoside and a naturally occurring polyphenol found abundantly in the plants of genus Mangifera particularly Mangifera indica L. and also in some medicinal herbs. Mangiferin exhibits antioxidant, antiviral, antitumor, anti-inflammatory and gene-regulatory effects and is considered to be of high research interest due to its therapeutic properties.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3128
BCCJ6806
BCCG0797
BCCF0341
BCCB4323

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Reversed-phase HPLC determination of mangiferin, isomangiferin and hesperidin in Cyclopia and the effect of harvesting date on the phenolic composition of C. genistoides
Joubert E, et al.
European Food Research and Technology, 216(3), 270-273 (2003)
S J Lin et al.
Journal of chromatography. A, 730(1-2), 17-23 (1996-04-12)
High-performance liquid chromatography was employed to determine the contents of several marker substances such as gentiopicroside, mangiferin, palmatine, berberine, baicalin, wogonin and glycyrrhizin in Sann-Joong-Kuey-Jian-Tang. The separation was performed on a Cosmosil 5C18-AR column by gradient elution with 0.03% (v/v)
High-performance liquid chromatographic method for the determination of mangiferin, likviritin and dihydroquercetin in rat plasma and urine
Geodakyan SV, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 577(2), 371-375 (1992)
Dandan Han et al.
Journal of pharmaceutical and biomedical analysis, 51(1), 260-263 (2009-08-25)
An ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method employing electrospray ionization (ESI) has been developed for the determination of mangiferin in rat plasma using diphenhydramine as the internal standard (IS). Liquid-liquid extraction (LLE) was used for sample preparation and
Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats
Muruganandan S, et al.
Journal of Ethnopharmacology, 97(3), 497-501 (2005)
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