Skip to Content
Merck
CN

16730

Sigma-Aldrich

2-Bromo-2-chloro-1,1,1-trifluoroethane

≥99.0% (GC)

Synonym(s):

Halothane

Sign Into View Organizational & Contract Pricing

Select a Size

About This Item

Linear Formula:
BrCH(Cl)CF3
CAS Number:
151-67-7
Molecular Weight:
197.38
Beilstein:
1736947
EC Number:
205-796-5
MDL number:
MFCD00009602
UNSPSC Code:
12352202
PubChem Substance ID:
329751365

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

vapor pressure

4.5 psi ( 20 °C)

Assay

≥99.0% (GC)

refractive index

n20/D 1.369 (lit.)
n20/D 1.369

bp

50.2 °C (lit.)

density

1.872 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

FC(F)(F)C(Cl)Br

InChI

1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H

InChI key

BCQZXOMGPXTTIC-UHFFFAOYSA-N

Gene Information

human ... ATP5D(513), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879), GLRA1(2741), GLRB(2743), GRIA1(2890), KCNK10(54207), KCNK18(338567), KCNK2(3776), KCNK3(3777), KCNK9(51305), KCNN4(3783)

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

2-Bromo-2-chloro-1,1,1-trifluoroethane is an inhalation anesthetic. In an effect believed to be independent of anesthesia, halothane inhibits the synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.
Inhalation anesthetic.

Signal Word

Danger

Hazard Statements

H315,H318,H335,H360

Hazard Classifications

Eye Dam. 1 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Shinya Endo et al.
Toxicology, 319, 75-84 (2014-03-07)
MicroRNAs (miRNA) form a class of small non-coding RNA molecules that negatively regulate gene expression. Most cellular pathways are modulated by miRNAs. However, the pathophysiological role of miRNAs during drug-induced liver injury (DILI) remains largely unknown. In this study, the
Hilmi Orhan et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 18(1), 73-81 (2012-11-10)
To investigate whether lipid and protein oxidation products are elevated and correlated with routine clinical markers of hepatic and renal function in patients anesthetized with halothane, isoflurane, or sevoflurane. Urine and blood samples were collected from patient groups. Excretion of
Travis J A Craddock et al.
PloS one, 7(6), e37251-e37251 (2012-07-05)
The cytoskeleton is essential to cell morphology, cargo trafficking, and cell division. As the neuronal cytoskeleton is extremely complex, it is no wonder that a startling number of neurodegenerative disorders (including but not limited to Alzheimer's disease, Parkinson's disease and
William R Proctor et al.
Hepatology (Baltimore, Md.), 57(5), 2026-2036 (2012-12-15)
Drug-induced liver injury (DILI) is a major health issue, as it remains difficult to predict which new drugs will cause injury and who will be susceptible to this disease. This is due in part to the lack of animal models
Albert Quintana et al.
PloS one, 7(8), e42904-e42904 (2012-08-23)
Anesthetics are in routine use, yet the mechanisms underlying their function are incompletely understood. Studies in vitro demonstrate that both GABA(A) and NMDA receptors are modulated by anesthetics, but whole animal models have not supported the role of these receptors
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service