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Merck
CN

34908

Dichloromethane

≥99.8% (GC)

Synonym(s):

Methylene chloride

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About This Item

Empirical Formula (Hill Notation):
CH2Cl2
CAS Number:
Molecular Weight:
84.93
EC Number:
200-838-9
UNSPSC Code:
12190000
MDL number:
Beilstein/REAXYS Number:
1730800
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vapor density

2.9 (vs air)

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

assay

≥99.8% (GC)

autoignition temp.

1223 °F

contains

~25 mg/L amylene as stabilizer

expl. lim.

22 %

technique(s)

UV/Vis spectroscopy: suitable

impurities

≤0.001% free acid (as HCl), ≤0.001% non-volatile matter, ≤0.02% water (Karl Fischer), ≤1 ppb fluorescence (quinine) at 254 nm, ≤1 ppb fluorescence (quinine) at 365 nm

transmittance

230 nm, ≥5%, 240 nm, ≥70%, 250 nm, ≥95%, 255 nm, ≥98%

refractive index

n20/D 1.424 (lit.)

bp

39.8-40 °C (lit.)

mp

−95 °C (lit.)

density

1.325 g/mL at 25 °C (lit.)

suitability

passes test for IR spectroscopy, passes test for suitability for UV spectroscopy

SMILES string

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N



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pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 2

flash_point_f

does not flash

flash_point_c

does not flash

ppe

Eyeshields, Faceshields, Gloves

Regulatory Information

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Iu V Plekhanova et al.
Prikladnaia biokhimiia i mikrobiologiia, 49(2), 203-208 (2013-06-26)
Cells of dichloromethane (DChM) bacteria-destructors were immobilized by sorption on different types of membranes, which were fixed on the measuring surface of a pH-sensitive field transistor. The presence of DChM in the medium (0.6-8.8 mM) led to a change in
M Soledade C Pedras et al.
Bioorganic & medicinal chemistry letters, 23(2), 484-487 (2012-12-13)
The phytoalexin cyclobrassinin is a plant defense that has additional importance since it inhibits brassinin hydrolase, a phytoalexin detoxifying enzyme produced by the plant pathogen Alternaria brassicicola. Hence, the 1,3-thiazino[6,5-b]indole scaffold of cyclobrassinin has great application as a lead structure
Mom Khay et al.
Natural product communications, 7(10), 1259-1262 (2012-11-20)
The extracts of five Cambodian medicinal plants (Aganosma marginata, Dracaena cambodiana, Harrisonia perforata, Hymenodictyon excelsum and Vernonia cinerea) were evaluated in vitro for their cytotoxic activity against HT29 colon adenocarcinoma cells and HepG2 hepatoma cells, using the MTT assay. Among