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About This Item
Empirical Formula (Hill Notation):
C12H14N2O5
CAS Number:
Molecular Weight:
266.25
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
224-261-7
MDL number:
Beilstein/REAXYS Number:
2816320
Product Name
N-(4-Aminobenzoyl)-L-glutamic acid, ≥98% (TLC)
Quality Level
assay
≥98% (TLC)
form
powder
color
off-white to beige
mp
175 °C (dec.)
application(s)
detection
peptide synthesis
storage temp.
−20°C
SMILES string
Nc1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
InChI
1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m0/s1
InChI key
GADGMZDHLQLZRI-VIFPVBQESA-N
Application
N-(4-Aminobenzoyl)-L-glutamic acid (ABG) is used as a strong UV absorbing tag for the derivitization of oligosaccharides to enhance their detection in analytical methods such as capillary zone electrophoresis (CZE).
Biochem/physiol Actions
N-p-Aminobenzoyl)-L-glutamic acid is a folate catabolite that can be metabolized by bacterial p-aminobenzoate auxotrophs possessing the enzyme p-aminobenzoyl-glutamate hydrolase.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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J Plocek et al.
Journal of chromatography. A, 757(1-2), 215-223 (1997-01-03)
A charged and strongly UV-absorbing tag, N-(4-aminobenzoyl)-L-glutamic acid) (ABG), was coupled to oligosaccharides by reductive amination under mild conditions. The effectiveness of ABG as a derivatization agent is shown through the separation of isomaltooligosaccharides from a dextran hydrolysate. The minimum
SreeDivya Saladi et al.
Molecular cell, 77(1), 189-202 (2019-11-02)
The proteolytic turnover of mitochondrial proteins is poorly understood. Here, we used a combination of dynamic isotope labeling and mass spectrometry to gain a global overview of mitochondrial protein turnover in yeast cells. Intriguingly, we found an exceptionally high turnover
J R Higgins et al.
BJOG : an international journal of obstetrics and gynaecology, 107(9), 1149-1154 (2000-09-26)
To estimate the rate of folate catabolism in pregnant and nonpregnant women and to derive the recommended dietary allowance for folate. Prospective, observational study. Rotunda Hospital, Dublin. WOMEN: Twenty-four healthy gravid women were studied once during each trimester and postpartum.
J F Gregory et al.
The Journal of nutrition, 131(7), 1928-1937 (2001-07-04)
To investigate the effects of pregnancy on folate metabolism, we conducted an 84-d study in second-trimester (gestational wk 14-25) pregnant women (n = 6) and nonpregnant controls (n = 6) with stable-isotopic tracer methods. All subjects were fed a diet
Rita Hannisdal et al.
The Journal of nutrition, 139(7), 1415-1418 (2009-05-22)
Folate is not stable in serum and plasma. This may impair laboratory diagnostics and distort the outcome of epidemiological studies on folate and chronic diseases. The present study was designed to determine the kinetics of folate loss in human serum
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A0879-5G | 04061833334553 |
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