A3711
AA-861
≥98% (HPLC)
Synonym(s):
2-(12-Hydroxydodeca-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone
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About This Item
Empirical Formula (Hill Notation):
C21H26O3
CAS Number:
Molecular Weight:
326.43
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
SMILES string
CC1=C(C)C(=O)C(CCCCC#CCCCC#CCO)=C(C)C1=O
assay
≥98% (HPLC)
solubility
ethanol: soluble
storage temp.
2-8°C
Gene Information
human ... ALOX5(240)
rat ... Alox5(25290)
Biochem/physiol Actions
5-Lipoxygenase inhibitor.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Yuzuru Itoh et al.
Science (New York, N.Y.), 340(6128), 75-78 (2013-04-06)
The 21st amino acid, selenocysteine (Sec), is synthesized on its cognate transfer RNA (tRNA(Sec)). In bacteria, SelA synthesizes Sec from Ser-tRNA(Sec), whereas in archaea and eukaryotes SepSecS forms Sec from phosphoserine (Sep) acylated to tRNA(Sec). We determined the crystal structures
Diego Romero et al.
Chemistry & biology, 20(1), 102-110 (2013-01-29)
Bacteria establish stable communities, known as biofilms, that are resistant to antimicrobials. Biofilm robustness is due to the presence of an extracellular matrix, which for several species-among them Bacillus subtilis-includes amyloid-like protein fibers. In this work, we show that B.
Lisa M Willis et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(51), 20753-20758 (2013-12-05)
Capsular polysaccharides (CPSs) are high-molecular-mass cell-surface polysaccharides, that act as important virulence factors for many pathogenic bacteria. Several clinically important Gram-negative pathogens share similar systems for CPS biosynthesis and export; examples include Escherichia coli, Campylobacter jejuni, Haemophilus influenzae, Neisseria meningitidis
Yuzuru Itoh et al.
Journal of molecular biology, 426(8), 1723-1735 (2014-01-25)
The 21st amino acid, selenocysteine (Sec), is incorporated translationally into proteins and is synthesized on its specific tRNA (tRNA(Sec)). In Bacteria, the selenocysteine synthase SelA converts Ser-tRNA(Sec), formed by seryl-tRNA synthetase, to Sec-tRNA(Sec). SelA, a member of the fold-type-I pyridoxal
Yajun Liu et al.
The Journal of biological chemistry, 287(53), 44406-44417 (2012-11-08)
Catechins (flavan-3-ols), the most important secondary metabolites in the tea plant, have positive effects on human health and are crucial in defense against pathogens of the tea plant. The aim of this study was to elucidate the biosynthetic pathway of
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