A3711
AA-861
≥98% (HPLC)
Synonym(s):
2-(12-Hydroxydodeca-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone
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About This Item
Empirical Formula (Hill Notation):
C21H26O3
CAS Number:
Molecular Weight:
326.43
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥98% (HPLC)
solubility
ethanol: soluble
storage temp.
2-8°C
SMILES string
CC1=C(C)C(=O)C(CCCCC#CCCCC#CCO)=C(C)C1=O
Gene Information
human ... ALOX5(240)
rat ... Alox5(25290)
Biochem/physiol Actions
5-Lipoxygenase inhibitor.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Yuzuru Itoh et al.
Science (New York, N.Y.), 340(6128), 75-78 (2013-04-06)
The 21st amino acid, selenocysteine (Sec), is synthesized on its cognate transfer RNA (tRNA(Sec)). In bacteria, SelA synthesizes Sec from Ser-tRNA(Sec), whereas in archaea and eukaryotes SepSecS forms Sec from phosphoserine (Sep) acylated to tRNA(Sec). We determined the crystal structures
Diego Romero et al.
Chemistry & biology, 20(1), 102-110 (2013-01-29)
Bacteria establish stable communities, known as biofilms, that are resistant to antimicrobials. Biofilm robustness is due to the presence of an extracellular matrix, which for several species-among them Bacillus subtilis-includes amyloid-like protein fibers. In this work, we show that B.
Lisa M Willis et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(51), 20753-20758 (2013-12-05)
Capsular polysaccharides (CPSs) are high-molecular-mass cell-surface polysaccharides, that act as important virulence factors for many pathogenic bacteria. Several clinically important Gram-negative pathogens share similar systems for CPS biosynthesis and export; examples include Escherichia coli, Campylobacter jejuni, Haemophilus influenzae, Neisseria meningitidis
Leandro Quadrana et al.
Plant molecular biology, 81(3), 309-325 (2012-12-19)
Tocopherols, compounds with vitamin E (VTE) activity, are potent lipid-soluble antioxidants synthesized only by photosynthetic organisms. Their biosynthesis requires the condensation of phytyl-diphosphate and homogentisate, derived from the methylerythritol phosphate (MEP) and shikimate pathways (SK), respectively. These metabolic pathways are
Tariq A Akhtar et al.
The Plant journal : for cell and molecular biology, 73(4), 640-652 (2012-11-09)
cis-prenyltransferases (CPTs) are predicted to be involved in the synthesis of long-chain polyisoprenoids, all with five or more isoprene (C5) units. Recently, we identified a short-chain CPT, neryl diphosphate synthase (NDPS1), in tomato (Solanum lycopersicum). Here, we searched the tomato
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