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Merck
CN

A6655

Aflatoxin B₁−BSA Conjugate

from Aspergillus flavus, powder, hepatotoxic mycotoxin

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
Form:
powder
Quality level:
Technical Service
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Product Name

Aflatoxin B1−BSA Conjugate from Aspergillus flavus,

form

powder

Quality Level

extent of labeling

8-12 mol Aflatoxin B1 per mol BSA

storage temp.

2-8°C

General description

Aflatoxin B1 is the most toxic aflatoxin. Aflatoxins are hepatotoxic metabolites, that are produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins contaminate human food and animal feed. They are linked to liver cancer, immune system suppression, reduced growth rates, losses in feed efficiency and death. They are naturally found toxic carcinogens and the most widely known mycotoxins. They mainly contaminate fruits, vegetables and grains.

Application

Aflatoxin B1-BSA Conjugate from Aspergillus flavus has been used in immunization of mice with phage and synthetic peptide. It is also used as a target molecule in si field-effect transistor (FET) biosensing techniques.
Aflatoxin B1 is a carcinogenic compound that induces transversion of G to T at codon 249 of the p53 tumor suppressor gene.

Disclaimer

Possibly carcinogenic.


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens (2008)
Morvarid Karamkhani et al.
Environmental monitoring and assessment, 192(7), 472-472 (2020-07-02)
Many workers are exposed to health problems arising from molds, fungi, and their toxins during waste processing. Aflatoxin B1 (AFB1) level in airborne and settled dust, aflatoxin B1-albumin (AFB1-Alb) adduct in serum, liver and kidney biochemical tests, and body redox
Detection of uncharged or feebly charged small molecules by field-effect transistor biosensors
Ah CS, et al.
Biosensors And Bioelectronics, 33(1), 233-240 (2012)



Global Trade Item Number

SKUGTIN
A6655-5MG04061833382592