A8230
Anti-Axin1 antibody produced in rabbit
~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-Axin, Anti-Axis Inhibitor-1, Anti-Axis inhibition protein 1
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About This Item
UNSPSC Code:
12352203
MDL number:
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~130 kDa
species reactivity
mouse, rat
concentration
~1.5 mg/mL
technique(s)
western blot: 0.5-1 μg/mL using HEK-293 cells expressing mouse FLAG-axin1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
mouse ... Axin1(12005)
rat ... Axin1(79257)
General description
Axin1 (axis inhibitor-1 or axin) functions as a negative regulator of Wnt signaling. Axin1 is known to associate with several members of the Wnt pathway such as β-catenin, glycogen synthase kinase-3β (GSK-3β), dishevelled (Dsh) and adenomatous polyposis coli (APC).
Anti-Axin1 recognizes mouse and rat axin1. Staining of the axin1 band in immunoblotting is specifically inhibited by the immunizing peptide.
Anti-Axin1 recognizes mouse and rat axin1. Staining of the axin1 band in immunoblotting is specifically inhibited by the immunizing peptide.
Immunogen
synthetic peptide corresponding to amino acids 604-624 located in the C-terminal region of rat axin1, conjugated to KLH. This sequence is highly conserved (single amino acid substitution) in mouse Axin1 and human has 76% identity.
Application
Immunohistochemistry of mouse brain section was performed using rabbit anti-axin1 antibody. Axin1 showed nuclear and cytplasmic expression in the soma and axons of neurons.
Rabbit Anti-Axin1 antibody can be used for western blot applications at concentrations 0.5-1μg/ml.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
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