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Merck
CN

AV32301

Sigma-Aldrich

Anti-THRAP5 antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-Thyroid hormone receptor associated protein 5

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

97 kDa

species reactivity

pig, human

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_005472

UniProt accession no.

Q9Y2X0

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... THRAP5(10025)

Related Categories

General description

THRAP5 (MED16) is a component of the Mediator complex required for facilitating the functions of transcriptional activators. This component is known to function as a coactivator for heat-shock-induced and lipopolysaccharide transcriptional stimulators.
Rabbit Anti-MED16 antibody recognizes human, mouse, rat, and canine MED16.

Immunogen

Synthetic peptide directed towards the C terminal region of human THRAP5

Application

Rabbit Anti-THRAP5 antibody can be used for western blot (0.12μg/ml) and IHC (4-8μg/ml) assays.

Biochem/physiol Actions

THRAP5 is part of the human thyroid hormone receptor-associated protein (TRAP)-Mediator family which acts as a coactivator for a broad range of nuclear hormone receptors as well as other classes of transcriptional activators.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: RLQFGRAPTLPGSAATLQLDGLARAPGQPKIDHLRRLHLGACPTEECKAC

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
QC1756

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Tae Whan Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(33), 12153-12158 (2004-08-07)
Transcriptional activators interact with diverse proteins and recruit transcriptional machinery to the activated promoter. Recruitment of the Mediator complex by transcriptional activators is usually the key step in transcriptional activation. However, it is unclear how Mediator recognizes different types of

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