AV32301
Anti-THRAP5 antibody produced in rabbit
IgG fraction of antiserum
Synonym(s):
Anti-Thyroid hormone receptor associated protein 5
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
1
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
97 kDa
species reactivity
pig, human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... THRAP5(10025)
General description
THRAP5 (MED16) is a component of the Mediator complex required for facilitating the functions of transcriptional activators. This component is known to function as a coactivator for heat-shock-induced and lipopolysaccharide transcriptional stimulators.
Rabbit Anti-MED16 antibody recognizes human, mouse, rat, and canine MED16.
Rabbit Anti-MED16 antibody recognizes human, mouse, rat, and canine MED16.
Immunogen
Synthetic peptide directed towards the C terminal region of human THRAP5
Application
Rabbit Anti-THRAP5 antibody can be used for western blot (0.12μg/ml) and IHC (4-8μg/ml) assays.
Biochem/physiol Actions
THRAP5 is part of the human thyroid hormone receptor-associated protein (TRAP)-Mediator family which acts as a coactivator for a broad range of nuclear hormone receptors as well as other classes of transcriptional activators.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: RLQFGRAPTLPGSAATLQLDGLARAPGQPKIDHLRRLHLGACPTEECKAC
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Tae Whan Kim et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(33), 12153-12158 (2004-08-07)
Transcriptional activators interact with diverse proteins and recruit transcriptional machinery to the activated promoter. Recruitment of the Mediator complex by transcriptional activators is usually the key step in transcriptional activation. However, it is unclear how Mediator recognizes different types of
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