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Merck
CN

AV44103

Sigma-Aldrich

Anti-SLC23A3 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-E2BP3, Anti-FLJ31168, Anti-SVCT3, Anti-Solute carrier family 23 (nucleobase transporters), member 3, Anti-Yspl1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

52 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_653313

UniProt accession no.

Q6PIS1-2

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... SLC23A3(151295)

Immunogen

Synthetic peptide directed towards the N terminal region of human SLC23A3

Application

Anti-SLC23A3 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.

Biochem/physiol Actions

SLC23A3 (SVCT3) is a Na(+)-dependent vitamin C (ascorbic acid) transporter belonging to the SLC23 family. It is expressed in the kidney and, like the other members of SLC23 family, is involved in maintaining the balance of vitamin C and its oxidized form dehydroascorbate (DHA) in the body.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: SRSPLNPSQLRSVGSQDALAPLPPPAPQNPSTHSWDPLCGSLPWGLSCLL

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
QC14497

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Shahar Biechonski et al.
International journal of cancer, 140(4), 864-876 (2016-11-05)
Quercetin (Que) is an abundant flavonoid in the human diet and high-concentration food supplement with reported pro- and anti-carcinogenic activities. Topoisomerase II (TopoII) inhibition and subsequent DNA damage induction by Que was implicated in the mixed lineage leukemia gene (MLL)
Marc Bürzle et al.
Current topics in membranes, 70, 357-375 (2012-11-28)
Vitamin C (ascorbic acid) is required for the synthesis of collagen, carnitine, catecholamine and the neurotransmitter norepinephrine. Vitamin C also plays an important role in protection against oxidative stress. Transporters for vitamin C and its oxidized form dehydroascorbate (DHA) are
Marc Bürzle et al.
Molecular aspects of medicine, 34(2-3), 436-454 (2013-03-20)
Transporters for vitamin C and its oxidized form dehydroascorbic acid (DHA) are crucial to maintain physiological concentrations of this important vitamin that is used in a variety of biochemical processes. The human SLC23 family consists of the Na(+)-dependent vitamin C

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