AV49710
Anti-POPDC3 antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Anti-MGC22671, Anti-POP3, Anti-Popeye domain containing 3, Anti-bA355M14.1
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
4
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
34 kDa
species reactivity
dog, rat, bovine, guinea pig, rabbit, human, horse, mouse
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... POPDC3(64208)
General description
The gene Popeye domain containing 3 (POPDC3; POP3) is mapped to human chromosome 6q21. POPDC3 is a transmembrane protein expressed in cardiac and skeletal muscles. It belongs to POPDC gene family.
Immunogen
Synthetic peptide directed towards the C terminal region of human POPDC3
Application
Anti-POPDC3 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
Biochem/physiol Actions
The expression of Popeye domain containing 3 (POPDC3; POP3) is essential for the development of cardiac and skeletal tissues during the development of vertebrates. POPDC3 is identified as a cAMP binding protein. Decrease in the expression of POPDC3 due to promoter hypermethylation correlates with poor prognosis of gastric cancer.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: YLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKRYHYDIRLPNFYQ
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Thomas Brand et al.
Biochemical Society transactions, 42(2), 295-301 (2014-03-22)
Popdc (Popeye-domain-containing) genes encode membrane-bound proteins and are abundantly present in cardiac myocytes and in skeletal muscle fibres. Functional analysis of Popdc1 (Bves) and Popdc2 in mice and of popdc2 in zebrafish revealed an overlapping role for proper electrical conduction
Mirang Kim et al.
Carcinogenesis, 31(9), 1685-1693 (2010-07-16)
The Popeye domain-containing (POPDC) genes BVES, POPDC2 and POPDC3 encode proteins that regulate cell-cell adhesion and cell migration during development. Herein, we report the frequent downregulation of BVES and POPDC3 by promoter hypermethylation in gastric cancer. POPDC expression in 11
Deng Luo et al.
World journal of gastroenterology, 18(19), 2423-2429 (2012-06-02)
To investigate the expression of Popeye domain containing 3 (Popdc3) and its correlation with clinicopathological features and prognosis of gastric cancer. The method of immunohistochemistry was used to investigate the expression of Popdc3 in 306 cases of human gastric cancer
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AV49710-100UL | 04061836206956 |