Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C17H17NO3
CAS Number:
Molecular Weight:
283.32
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Product Name
BW A4C, ≥98% (HPLC)
InChI key
CEUDWZXMLMKPNN-SOFGYWHQSA-N
SMILES string
CC(=O)N(O)C\C=C\c1cccc(Oc2ccccc2)c1
InChI
1S/C17H17NO3/c1-14(19)18(20)12-6-8-15-7-5-11-17(13-15)21-16-9-3-2-4-10-16/h2-11,13,20H,12H2,1H3/b8-6+
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white
mp
79.3-80.1 °C (lit.)
solubility
DMSO: 20 mg/mL
storage temp.
2-8°C
Quality Level
Gene Information
human ... ALOX5(240)
rat ... Alox5(25290)
Related Categories
Biochem/physiol Actions
Selective 5-lipoxygenase (5-LOX) inhibitor. Inhibits synthesis of LTB4.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
G Valen et al.
Free radical biology & medicine, 15(1), 27-35 (1993-07-01)
The role of arachidonic acid metabolites in the cardiac effects of toxic oxygen metabolites (TOM) was investigated in buffer-perfused rat hearts (Langendorff model). Hydrogen peroxide (H2O2, 200 microM) was given for 10 min to generate TOM, followed by 30 min
Francisco Airton Castro da Rocha et al.
European journal of pharmacology, 497(1), 81-86 (2004-08-24)
We investigated whether leukotrienes mediate cell influx and articular incapacitation in zymosan-induced arthritis. Rats received 1 mg zymosan intra-articularly (i.a.). The hyperalgesia was measured using the rat articular incapacitation test. Cell influx, leukotriene B(4) and prostaglandin E(2) levels were assessed
M Ayyub Khan et al.
Leukemia research, 17(3), 241-245 (1993-03-01)
The proliferation of malignant hemopoietic cell lines is inhibited by antagonists of 5-lipoxygenase, suggesting that the endogenous generation of leukotrienes via the action of this enzyme may play some role in the proliferation of these cells (Snyder D. S., Castro
R G Cooke et al.
Research in veterinary science, 64(3), 263-264 (1998-08-05)
The effect of an intra-luteal injection of the 5-lipoxygenase (5-LO) inhibitor BWA4C (2 mg in 50 microl DMSO) on the secretion of oxytocin (OT) from the corpus luteum in response to a close-arterial infusion of prostaglandin (PG)-F2alpha (5 ng min(-1))
H J Hussey et al.
British journal of cancer, 70(1), 6-10 (1994-07-01)
The effect of the polyunsaturated fatty acids (PUFAs) linoleic acid (LA) and arachidonic acid (AA) on the growth of two murine colon adenocarcinoma cell lines (MAC26 and MAC13) has been determined both in vitro and in vivo. When the serum
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service