D3689
(S)-3,5-Dihydroxyphenylglycine hydrate
≥98% (HPLC), group I metabotropic glutamate receptor agonist, powder
Synonym(s):
S-DHPG
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About This Item
Empirical Formula (Hill Notation):
C8H9NO4 · xH2O
CAS Number:
Molecular Weight:
183.16 (anhydrous basis)
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
Storage condition:
desiccated, protect from light
Product Name
(S)-3,5-Dihydroxyphenylglycine hydrate, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
storage condition
desiccated, protect from light
color
white
storage temp.
−20°C
SMILES string
O.N[C@H](C(O)=O)c1cc(O)cc(O)c1
InChI
1S/C8H9NO4.H2O/c9-7(8(12)13)4-1-5(10)3-6(11)2-4;/h1-3,7,10-11H,9H2,(H,12,13);1H2/t7-;/m0./s1
InChI key
QZEFIWWBQUKNFA-FJXQXJEOSA-N
Gene Information
human ... GRM1(2911)
Application
(S)-3,5-Dihydroxyphenylglycine hydrate has been used:
- as mGluR1/5 agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations
- in ACSF for DHPG stimulation
- to inject into basolateral amygdala to study its effect on memory expression
Biochem/physiol Actions
(S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Disclaimer
air sensitive
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Articles
DISCOVER Bioactive Small Molecules for Neuroscience
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Spinocerebellar ataxias (SCAs) are a group of hereditary neurodegenerative diseases which are caused by diverse genetic mutations in a variety of different genes. We have identified RGS8, a regulator of G-protein signaling, as one of the genes which are dysregulated
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D3689-10MG | 04061832081892 |
| D3689-5MG | 04061832081908 |