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Merck
CN

D4159

cis-13,16-Docosadienoic acid

~99% (capillary GC)

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About This Item

Empirical Formula (Hill Notation):
C22H40O2
CAS Number:
Molecular Weight:
336.55
UNSPSC Code:
12352211
PubChem Substance ID:
MDL number:
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SMILES string

CCCCC\C=C\C\C=C\CCCCCCCCCCCC(O)=O

assay

~99% (capillary GC)

storage temp.

−20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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J M Muderhwa et al.
The Journal of biological chemistry, 267(34), 24184-24192 (1992-12-05)
Pancreatic carboxylester lipase catalyzes the exchange of 18O between water and 13,16-cis,cis-doco-sadienoic acid (DA) in monolayers at the argon-buffer interface (Muderhwa, J.M., Schmid, P.C., and Brockman, H.L. (1992) Biochemistry 31, 141). In mixed monolayers of 18O, 18O-DA and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)
G D Schmit et al.
Biophysical journal, 71(6), 3421-3429 (1996-12-01)
It has been suggested that at physiological pH, the trypsin-catalyzed activation of the lipase cofactor, procolipase, to colipase has no consequence for intestinal lipolysis and serves primarily to release the N-terminal pentapeptide, enterostatin, a satiety factor (Larsson, A., and C.
M Dahim et al.
Biochemistry, 37(23), 8369-8377 (1998-06-19)
Colipase is a cofactor protein which forms a 1:1 complex with pancreatic lipase. This facilitates lipase adsorption to phosphatidylcholine-rich interfaces, presumably as a consequence of the higher affinity of colipase for such interfaces. According to this model, the presence of
J M Smaby et al.
Biochemistry, 33(7), 1915-1922 (1994-02-22)
Lipase-catalyzed oxygen exchange between 13,16-cis,cis-docosadienoic acid and water in liquid-expanded monolayers with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine exhibits abrupt, lipid composition-dependent changes in extent and mechanism [e.g., Muderhwa, J. M. and Brockman, H. L. (1992) J. Biol. Chem. 267, 24184-24192]. The critical nature of
Claire Denis et al.
Lipids, 44(7), 655-663 (2009-03-07)
The phospholipid fatty acid composition of the North-East Atlantic sponge Polymastia penicillus (South Brittany, France) was investigated. Sixty fatty acids (FA) were identified as methyl esters (FAME) and N-acyl pyrrolidides (NAP) by gas chromatography-mass spectrometry (GC/MS), including eight Delta5,9 unsaturated

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