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Merck
CN

G017

(±)-AMPA hydrobromide

solid

Synonym(s):

(±)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C7H10N2O4 · HBr
CAS Number:
171259-81-7
Molecular Weight:
267.08
UNSPSC Code:
12352200
PubChem Substance ID:
24277979
MDL number:
MFCD00055183

Key Documents

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form

solid

color

white

solubility

H2O: 1.2 mg/mL, ethanol: 1.8 mg/mL, DMSO: 16 mg/mL

storage temp.

2-8°C

SMILES string

Br.Cc1onc(O)c1CC(N)C(O)=O

InChI

1S/C7H10N2O4.BrH/c1-3-4(6(10)9-13-3)2-5(8)7(11)12;/h5H,2,8H2,1H3,(H,9,10)(H,11,12);1H

InChI key

KUAHVIUZGLGASU-UHFFFAOYSA-N

Gene Information

human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIK5(2901)

Biochem/physiol Actions

(±)-AMPA is a potent excitatory amino acid that interacts selectively with central AMPA/kainate receptors.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Excitatory amino acid receptors in the vertebrate central nervous system.
G L Collingridge et al.
Pharmacological reviews, 41(2), 143-210 (1989-06-01)
Structural, conformational, and stereochemical requirements of central excitatory amino acid receptors.
J J Hansen et al.
Medicinal research reviews, 10(1), 55-94 (1990-01-01)

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