CN
GRIA4
glutamate receptor, ionotropic, AMPA 4
别名:
GLUR4, GLUR4C, GLURD, GluA4
物种:
Human GRIA4 (2893), Mouse Gria4 (14802), Rat Gria4 (29629), sheep GRIA4 (443274), domestic cat GRIA4 (101087003), chicken GRIA4 (396137), domestic guinea pig Gria4 (100728256), cow GRIA4 (529904), Horse GRIA4 (100061561), dog GRIA4 (489427)
UniProtKB ID:
基因ID:
- Human(2893) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
- Mouse(14802) glutamate receptor, ionotropic, AMPA4 (alpha 4)
- Rat(29629) glutamate receptor, ionotropic, AMPA 4
- sheep(443274) glutamate receptor, ionotropic, AMPA 4
- domestic cat(101087003) glutamate receptor, ionotropic, AMPA 4
- chicken(396137) glutamate receptor, ionotropic, AMPA 4
- domestic guinea pig(100728256) glutamate receptor, ionotropic, AMPA 4
- cow(529904) glutamate receptor, ionotrophic, AMPA 4
- Horse(100061561) glutamate receptor, ionotropic, AMPA 4
- dog(489427) glutamate receptor, ionotropic, AMPA 4
- naked mole-rat(101698538) glutamate receptor, ionotropic, AMPA 4
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Small Molecule - Antagonist
Antibodies
货号
说明
物种反应性
应用
抗谷氨酸受体4抗体, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-GluR4/GluA4/GRIA4 Antibody, clone 4M5D0, Rabbit Monoclonal, ,
物种反应性
mouse, rat
应用
western blot
Anti-GLUR4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Anti-phospho GluR4 (Ser842) Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse, rat
应用
western blot
Anti-GRIA4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
bovine, human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
货号
说明
物种
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human