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H128

(R)(−)-α-Methylhistamine dihydrochloride

Name: (R)(&#8722;)-&#945;-Methylhistamine dihydrochloride
Brand: SIGMA

≥98% (HPLC), Histamine receptor agonist, solid

Synonym(s):

(R)(−)-α-Methyl-1H-imidazole-4-ethanamine dihydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₁N₃ · 2HCl

CAS Number:

75614-89-0

Molecular Weight:

198.09

UNSPSC Code:

12352116

PubChem Substance ID:

24277778

NACRES:

NA.77

MDL number:

MFCD00083176

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

desiccated

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Properties

Product Name

(R)(−)-α-Methylhistamine dihydrochloride, solid, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

solid

optical activity

[α]22/D −4°, c = 0.8 in H₂O(lit.)

storage condition

desiccated

color

white to off-white

solubility

H₂O: soluble

SMILES string

Cl.Cl.C[C@@H](N)Cc1c[nH]cn1

InChI

1S/C6H11N3.2ClH/c1-5(7)2-6-3-8-4-9-6;;/h3-5H,2,7H2,1H3,(H,8,9);2*1H/t5-;;/m1../s1

InChI key

IZHCNQFUWDFPCW-ZJIMSODOSA-N

Gene Information

human ... HRH3(11255)

Description

Application

(R)(−)-α-Methylhistamine dihydrochloride has been used as an agonist for the histamine H3 cell lines. It has also been used in the antagonist assay for the histamine H3 cell lines.

Biochem/physiol Actions

(R)(−)-α-Methylhistamine dihydrochloride is a potent, selective H₃ histamine receptor agonist which crosses the blood-brain barrier. It can inhibit histamine synthesis and release.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c