H128
(R)(−)-α-Methylhistamine dihydrochloride
≥98% (HPLC), Histamine receptor agonist, solid
Synonym(s):
(R)(−)-α-Methyl-1H-imidazole-4-ethanamine dihydrochloride
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About This Item
Empirical Formula (Hill Notation):
C6H11N3 · 2HCl
CAS Number:
Molecular Weight:
198.09
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
Product Name
(R)(−)-α-Methylhistamine dihydrochloride, solid, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
solid
optical activity
[α]22/D −4°, c = 0.8 in H2O(lit.)
storage condition
desiccated
color
white to off-white
solubility
H2O: soluble
SMILES string
Cl.Cl.C[C@@H](N)Cc1c[nH]cn1
InChI
1S/C6H11N3.2ClH/c1-5(7)2-6-3-8-4-9-6;;/h3-5H,2,7H2,1H3,(H,8,9);2*1H/t5-;;/m1../s1
InChI key
IZHCNQFUWDFPCW-ZJIMSODOSA-N
Gene Information
human ... HRH3(11255)
Application
(R)(−)-α-Methylhistamine dihydrochloride has been used as an agonist for the histamine H3 cell lines. It has also been used in the antagonist assay for the histamine H3 cell lines.
Biochem/physiol Actions
(R)(−)-α-Methylhistamine dihydrochloride is a potent, selective H3 histamine receptor agonist which crosses the blood-brain barrier. It can inhibit histamine synthesis and release.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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