H7250
Histamine dihydrochloride
≥99% (TLC), powder, endogenous histamine receptor agonist
Synonym(s):
2-(4-Imidazolyl)ethylamine dihydrochloride
About This Item
Product Name
Histamine dihydrochloride, ≥99% (TLC), powder
Quality Level
Assay
≥99% (TLC)
form
powder
color
white to off-white
mp
249-252 °C (lit.)
storage temp.
2-8°C
SMILES string
Cl[H].Cl[H].NCCc1c[nH]cn1
InChI
1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H
InChI key
PPZMYIBUHIPZOS-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269), HRH2(3274)
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General description
Application
- as a orthograde cotransmitter in producing excitatory postsynaptic potential (EPSP)
- to determine its level in fish using HPLC (high performance liquid chromatography)
- to assess the tracheal response to antigens in guinea-pigs
Biochem/physiol Actions
Features and Benefits
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
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How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How should Product H7250, Histamine dihydrochloride, be dissolved?
We test the solubility of this product in water at a concentration of 50 mg/mL. This yields a clear, colorless to faint yellow solution.
How should Product H7250, Histamine dihydrochloride, be stored?
This product is a powder and should be stored at 2-8°C, dessicated.
What is the solution stablity of Product H7250, Histamine dihydrochloride?
Solutions can be stored at 2-4°C for 8 weeks, and at -20°C for up to 12 months. Once thawed, solutions should be used within 6 hours or discarded. Solutions are light sensitive and need to be protected from light.
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