I2516
Isocitric Dehydrogenase (NADP) from porcine heart
lyophilized powder, 20-60 units/mg protein (biuret)
Synonym(s):
threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH, IDH
form
lyophilized powder
specific activity
20-60 units/mg protein (biuret)
composition
Protein, ~20%
storage temp.
−20°C
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Physical form
Lyophilized powder containing sodium citrate and manganous sulfate
Analysis Note
Highly purified
Essentially free of aconitase activity.
Essentially free of aconitase activity.
Other Notes
One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37°C.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Resp. Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Isocitrate Dehydrogenases (IDHs) are important enzymes present in all living cells. Three subfamilies of functionally dimeric IDHs (subfamilies I, II, III) are known. Subfamily I are well-studied bacterial IDHs, like that of Escherischia coli. Subfamily II has predominantly eukaryotic members
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