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Merck
CN

SAB4501554

Sigma-Aldrich

Anti-INSL4 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

EPIL, Early placenta insulin-like peptide, Insulin-like peptide 4, Placentin

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 15 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000

NCBI accession no.

Q14641

UniProt accession no.

Q14641

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... INSL4(3641)

General description

Anti-INSL4 antibody detects endogenous levels of total INSL4 protein.
Early placental insulin-like protein (INSL4 or EPIL) belongs to the insulin superfamily of hormones. It is expressed at high level in the placenta. The gene encoding INSL4 is located on human chromosome 9p24 and consists of two exons and one intron.

Immunogen

The antiserum was produced against synthesized peptide derived from human INSL4.

Immunogen Range: 41-90

Biochem/physiol Actions

Early placental insulin-like protein (INSL4 or EPIL) helps in the development of placental and fetal membrane. It may play a major role in the progression trophoblast and regulation of bone formation.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
3115598

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Insulin-like 4 (INSL4) gene expression in human embryonic and trophoblastic tissues
Laurent A, et al.
Molecular Reproduction and Development, 51(2), 123-129 (1998)
Lynnae Millar et al.
Biology of reproduction, 73(4), 695-702 (2005-06-17)
Early placental insulin-like protein (INSL4 or EPIL) is a member of the insulin superfamily of hormones, which is highly expressed in the placenta. We have confirmed this at term and shown it to be expressed by the maternal decidua. Although

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