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Merck
CN

SAB4501638

Sigma-Aldrich

Anti-CA13 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

CA-XIII, Carbonate dehydratase XIII, Carbonic anhydrase 13, Carbonic anhydrase XIII

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 29 kDa

species reactivity

human, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI accession no.

Q8N1Q1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CAH13(377677)

Related Categories

General description

Anti-CA13 Antibody detects endogenous levels of total CA13 protein.
The gene CA13 (carbonic anhydrase 13) is mapped to human chromosome 8q21. The encoded protein belongs to the carbonic anhydrase family of proteins. It is present in the cytoplasm. CA13 is expressed in various tissues, such as salivary glands, kidney, small intestine, colon, uterus and testis.

Immunogen

The antiserum was produced against synthesized peptide derived from human CA13.

Immunogen Range: 141-190

Biochem/physiol Actions

The carbonic anhydrase (CA) family of proteins help in maintaining the pH homeostasis by causing reversible hydration of carbon dioxide. CA13 is downregulated in colorectal cancer.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
3114936

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Mika Hilvo et al.
Current topics in medicinal chemistry, 7(9), 893-899 (2007-05-17)
The carbonic anhydrase (CA) protein family consists of twelve active isozymes in humans and thirteen in most other mammals. The most recently discovered members of this family include cytosolic CA XIII and membrane-bound CAs XIV and XV. In this article
Laura Kummola et al.
BMC cancer, 5, 41-41 (2005-04-20)
Carbonic anhydrase (CA) isozymes may have an important role in cancer development. Some isozymes control pH homeostasis in tumors that appears to modulate the behaviour of cancer cells. CA XIII is the newest member of the CA gene family. It
M Hilvo et al.
Current pharmaceutical design, 14(7), 672-678 (2008-03-14)
The carbonic anhydrase (CA) enzyme family consists of thirteen active isozymes in mammals. The most recently characterized members of this family are cytosolic CA XIII and membrane-bound CA XV. This article describes recent advances in the CA family, especially CA

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