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SAB4502044

Anti-ZNF295 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

KIAA1227, ZBTB21, ZNF295, Zinc finger and BTB domain-containing protein 21, Zinc finger protein 295

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC
Citations:
2

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 118 kDa

species reactivity

mouse, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:10000, immunohistochemistry: 1:50-1:100

NCBI accession no.

Q9ULJ3

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ZNF295(49854)

Related Categories

General description

Anti-ZNF295 Antibody detects endogenous levels of total ZNF295 protein.
The gene ZBTB21 (zinc finger and BTB domain containing 21) is mapped to human chromosome 21q22.3. The protein contains a BTB (broad-complex, tramtrack and bric a brac)/POZ (poxvirus and zinc finger) domain and multiple kruppel (C2H2) type zinc finger domains. ZBTB21 is part of the POK (POZ and krüppel) transcription factor family of proteins. It is widely expressed in human tissues.

Immunogen

The antiserum was produced against synthesized peptide derived from human ZNF295.

Immunogen Range: 731-780

Biochem/physiol Actions

ZBTB21 (zinc finger and BTB domain containing 21) is a transcription repressor. It interacts with ZFP161 (zinc finger protein 161) and might be associated with the bi-directional control of gene expression.

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
3119596

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M Reza Sailani et al.
Genome research, 23(9), 1410-1421 (2013-06-21)
Congenital heart defect (CHD) occurs in 40% of Down syndrome (DS) cases. While carrying three copies of chromosome 21 increases the risk for CHD, trisomy 21 itself is not sufficient to cause CHD. Thus, additional genetic variation and/or environmental factors
Jun Wang et al.
Biochemical and biophysical research communications, 327(2), 615-627 (2005-01-05)
Human ZNF295 protein harbors a BTB/POZ domain and multiple krüppel (C(2)H(2)) type zinc finger domains, and thus belongs to a family of POK (POZ and krüppel) transcription factor. We have identified many transcript variants generated by the alternative splicing in

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