SAB5702072
Anti-SDHB Antibody, clone 9S1A0, Rabbit Monoclonal
Synonym(s):
CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
9S1A0, monoclonal
Application:
western blot
Species reactivity:
rat, rat, human
Citations:
Technique(s):
western blot: 1:500 - 1:2000
Uniprot accession no.:
material
colorless
biological source
rabbit
conjugate
unconjugated
clone
9S1A0, monoclonal
form
liquid
mol wt
32 kDa
species reactivity
rat, rat, human
concentration
0.19 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
DGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKASV
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SDHB(6390)
Application
WB
General description
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 181-280 of human SDHB (P21912).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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