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Merck
CN

SAB5702552

Sigma-Aldrich

Anti-p70 S6 Kinase 1 Antibody, clone 1S7Y4, Rabbit Monoclonal

Synonym(s):

PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

1S7Y4, monoclonal

form

liquid

mol wt

68 kDa

species reactivity

rat, human, rat

concentration

0.09 mg/mL

technique(s)

immunohistochemistry: 1:100 - 1:500
western blot: 1:1000 - 1:1800

color

colorless

isotype

IgG

immunogen sequence

MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKG

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RPS6KB1(6198)

General description

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p70 S6 Kinase 1 1 (P23443).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Information

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