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Key Documents

SAB5702731

Sigma-Aldrich

Anti-ITPA Antibody, clone 2O6K5, Rabbit Monoclonal

Synonym(s):

ITPA, C20orf37, HLC14-06-P, ITPase, My049, NTPase, dJ794I6.3, inosine triphosphatase

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

100

conjugate

unconjugated

material

colorless

clone

2O6K5, monoclonal

form

liquid

mol wt

21 kDa

species reactivity

mouse, mouse

concentration

1.50 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

VEDTCLCFNALGGLPGPYIKWFLEKLKPEGLHQLLAGFEDKSAYALCTFALSTGDPSQPVRLFRGRTSGRIVAPRGCQDFG

UniProt accession no.

Q9BY32

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ITPA(3704)

General description

This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 70-150 of human ITPA (Q9BY32).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

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