SAB5702787
Anti-Phospho-RB(pSer780) Antibody, clone 8R5F5, Rabbit Monoclonal
Synonym(s):
OSRC,PPP1R130,RB,p105-Rb,pRb,pp110,RB1,Rb
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
, human
Conjugate:
unconjugated
Application:
IHC, WB
Citations:
-
species reactivity
, human
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
8R5F5, monoclonal
form
liquid
mol wt
106 kDa
concentration
1.74 mg/mL
technique(s)
immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
TLSPI
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RB1(5925)
Related Categories
General description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic phosphorylated peptide around S780 of human RB (P06400).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
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