SCP0179
Leumorphin (Preproenkephalin B) 226-254 human
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About This Item
Empirical Formula (Hill Notation):
C150H224N42O46
Molecular Weight:
3351.64
UNSPSC Code:
12352202
NACRES:
NA.77
Assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Related Categories
Amino Acid Sequence
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-Arg-Ser-Gln-Glu-Asp-Pro-Asn-Ala-Tyr-Ser-Gly-Glu-Leu-Phe-Asp-Ala
Application
Leumorphin and prodynorphin are endogenous opioid polypeptide hormones used to study opioid signaling and opioid peptide metabolic processing.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Brigitte L Kieffer et al.
Progress in neurobiology, 66(5), 285-306 (2002-05-17)
The endogenous opioid system consists of three opioid peptide precursor genes encoding enkephalins (preproenkephalin, Penk), dynorphins (preprodynorphin, Pdyn) and beta-endorphin (betaend), proopiomelanocortin (POMC) and three receptor genes encoding mu-opiod receptor (MOR), delta-opiod receptor (DOR) and kappa-opiod receptor (KOR). In the
S R Ojeda et al.
Recent progress in hormone research, 55, 197-223 (2000-10-19)
It is becoming increasingly clear that astroglial cells are active participants in the process by which information is generated and disseminated within the central nervous system (CNS). In the hypothalamus, astrocytes regulate the secretory activity of neuroendocrine neurons. They contribute
Invertebrate opiate immune and neural signaling.
George B Stefano et al.
Advances in experimental medicine and biology, 521, 126-147 (2003-03-06)
Patrice G Guyenet et al.
Clinical and experimental pharmacology & physiology, 29(3), 238-242 (2002-03-22)
1. The present article reviews several aspects of opioid signalling in the rostral ventrolateral medulla (RVLM) and their implications for the neural control of blood pressure. 2. In the RVLM, preproenkephalin (PPE) mRNA is expressed by bulbospinal cells that are
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