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Merck
CN

SEP130

Seppro Rat

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
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capacity

1.2 mg total protein loading(26 μL of rat plasma, average rat protein concentration 45 mg/mL)

storage temp.

2-8°C

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General description

Immunoaffinity partitioning of highly-abundant proteins (HAP) has proven to be one of the most effective approaches for overcoming the wide dynamic range of plasma protein concentration, as well as enabling the detection of low-abundant proteins (LAP). Avian polyclonal IgY (Immunoglobulin Yolk) antibodies have unique and advantageous features that allow highly-specific partitioning of protein mixtures. Sigma offers a novel Seppro IgY-R7 column system, which takes you deeper into the rat plasma/serum proteome.

Proteins Partitioned:

Rat serum albumin
IgG
Fibrinogen
Transferrin
IgM
Haptoglobin
alpha1-Antitrypsin

Application

Seppro Rat, spin columns (15-20μL capacity) is designed for use as a plasma/serum protein removal tool base upon avian antibody (IgY)-antigen immune affinity removal of seven highly abundant proteins (HAP) from rat plasma protein mixtures via liquid chromatography. Seppro Rat, spin column is used to support the analysis of low abundance rat serum/plasma proteins.

Legal Information

Seppro is a trademark of Merck KGaA, Darmstadt, Germany

Kit Components Also Available Separately

Product No.
Description
SDS

  • S4199Seppro Dilution bufferSDS

  • S4324Seppro Stripping BufferSDS

  • S4449Seppro Neutralization BufferSDS

  • CLS8163Corning® Costar® Spin-X® centrifuge tube filters, cellulose acetate membrane, pore size 0.45 μm, non-sterileSDS

  • S4574Spin Column for SepproSDS

Storage Class

10 - Combustible liquids

Regulatory Information

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Michael E Hoover et al.
Journal of proteomics, 226, 103907-103907 (2020-07-25)
Heterotopic ossification (HO) is the formation of ectopic bone in soft tissues observed in patients following blast injuries, orthopedic or head trauma, burns, or in the context of inborn mutations of genes involved in osteogenesis. There is no universally accepted

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