T6704
Tandospirone
≥98% (HPLC)
Synonym(s):
(1R*,2S*,3R*,4S*)-N-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-2,3-norbornanedicarboximide citrate salt, SM 3997
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About This Item
Empirical Formula (Hill Notation):
C21H29N5O2
CAS Number:
Molecular Weight:
383.49
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Storage condition:
protect from light
Quality Segment
assay
≥98% (HPLC)
storage condition
protect from light
solubility
DMSO: 38 mg/mL
originator
Dainippon Sumitomo
storage temp.
2-8°C
SMILES string
O=C1[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2C(=O)N1CCCCN4CCN(CC4)c5ncccn5
InChI
1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18-
InChI key
CEIJFEGBUDEYSX-FZDBZEDMSA-N
Biochem/physiol Actions
Tandospirone is a partial agonist at 5HT1A receptors.
Tandospirone is a partial agonist at 5HT1A receptors. It significantly reduces haloperidol-induced bradykinesia in a dose-dependent manner. The potency of tandospirone is equal to that of buspirone and approximate half that of diazepam. The potency of tandospirone as a dopamine antagonistic is less than 1/4 that of buspirone.
Features and Benefits
This compound was developed by Dainippon Sumitomo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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