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Merck
CN

T6704

Tandospirone

≥98% (HPLC)

Synonym(s):

(1R*,2S*,3R*,4S*)-N-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-2,3-norbornanedicarboximide citrate salt, SM 3997

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About This Item

Empirical Formula (Hill Notation):
C21H29N5O2
CAS Number:
87760-53-0
Molecular Weight:
383.49
UNSPSC Code:
51111800
PubChem Substance ID:
329826853
NACRES:
NA.77

Key Documents

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Quality Level

100

SMILES string

O=C1[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2C(=O)N1CCCCN4CCN(CC4)c5ncccn5

InChI

1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18-

InChI key

CEIJFEGBUDEYSX-FZDBZEDMSA-N

assay

≥98% (HPLC)

storage condition

protect from light

solubility

DMSO: 38 mg/mL

originator

Dainippon Sumitomo

storage temp.

2-8°C

Related Categories

Biochem/physiol Actions

Tandospirone is a partial agonist at 5HT1A receptors.
Tandospirone is a partial agonist at 5HT1A receptors. It significantly reduces haloperidol-induced bradykinesia in a dose-dependent manner. The potency of tandospirone is equal to that of buspirone and approximate half that of diazepam. The potency of tandospirone as a dopamine antagonistic is less than 1/4 that of buspirone.

Features and Benefits

This compound was developed by Dainippon Sumitomo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000421042
0000421041
0000421042
0000421041
0000223810

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