20744AST
Astec® CYCLOBOND I 2000 DMP Chiral (5 μm) HPLC Columns
L × I.D. 25 cm × 21.2 mm, HPLC Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
25 cm × 21.2 mm
Particle size:
5 μm
Matrix active group:
cyclodextrin, beta- phase
Pore size:
100 Å
Matrix:
silica particle platform, fully porous particle
Product Name
Astec® CYCLOBOND I 2000 DMP Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 21.2 mm
material
stainless steel column
Quality Level
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-50 °C temperature, 172 bar pressure (2500 psi)
technique(s)
HPLC: suitable, LC/MS: suitable
L × I.D.
25 cm × 21.2 mm
matrix
silica particle platform, fully porous particle
matrix active group
cyclodextrin, beta- phase
particle size
5 μm
pore size
100 Å
operating pH
3.5-7
separation technique
chiral
General description
The reaction of the 3,5-dimethylphenyl isocyanate with the hydroxyl groups of β-cyclodextrin results in a pi-basic phase similar in character to the naphthylethyl carbamate phases. The selectivity is greater for the CYCLOBOND I 2000 DMP when the chiral center of the analyte is part of a ring structure or is on the α carbon. This phase has been very useful for derivatized amines, like amphetamine ACQ.
- Bonded phase: 3,5-Dimethylphenyl carbamate modified β-cyclodextrin
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
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Related Content
CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.
Reprint of: Enantiomeric separation of functionalized ethano-bridged Troger bases using macrocyclic cyclofructan and cyclodextrin chiral selectors in high-performance liquid chromatography and capillary electrophoresis with application of principal component analysis
Weatherly, Choyce A., et al.
Journal of Chromatography. B, Biomedical Applications, 968, 40-48 (2014)
István Ilisz et al.
Chirality, 21(3), 339-348 (2008-06-17)
The application of 3,5-dimethylphenyl-carbamoylated-beta-cyclodextrin (Cyclobond I 2000 DMP) and 2,6-dinitro-4-trifluoromethylphenyl-ether-beta-cyclodextrin-based (Cyclobond DNP) chiral stationary phases for the high-performance liquid chromatographic enantioseparation of unusual beta-amino acids is reported. The investigated amino acids were saturated or unsaturated alicyclic beta-3-homo-amino acids and bicyclic
Nilusha L T Padivitage et al.
Drug testing and analysis, 6(6), 542-551 (2013-10-12)
Recently a novel class of chiral stationary phases (CSPs) based on cyclofructan (CF) has been developed. Cyclofructans are cyclic oligosaccharides that possess a crown ether core and pendent fructofuranose moieties. Herein, we evaluate the applicability of these novel CSPs for
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 20744AST | 04061833514382 |