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40334

N-Nitrosodiethylamine (NDEA) solution

certified reference material, 5000 μg/mL in methanol

Synonym(s):

Diethylnitrosamine

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About This Item

CAS Number:
55-18-5
UNSPSC Code:
41116105
MDL number:
MFCD00013890
NACRES:
NA.24
Technical Service
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Quality Segment

300

product line

TraceCERT®

grade

certified reference material, TraceCERT®

CofA

current certificate can be downloaded

packaging

ampule of 1 mL

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

concentration

5000 μg/mL in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

single component solution

storage temp.

2-8°C

SMILES string

N(N=O)(CC)CC

InChI

1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3

InChI key

WBNQDOYYEUMPFS-UHFFFAOYSA-N

General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodiethylamine (NDEA) solution is commonly employed as a certified reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.

Application

N-Nitrosodiethylamine (NDEA) solution may be used as an analytical reference standard for the quantification of nitrosamine impurities and precursors in drug products using liquid gas chromatography-mass spectrometry (GC-MS).

Analysis Note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with  ISO 17034  and  ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

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